"The European Medicines Agency's Committee for Medicinal Products for Human Use (CHMP) has recommended the marketing of selexipag (Uptravi, Actelion Registration Ltd) for the treatment of adults with pulmonary arterial hypertension (PAH)./"...
Visken Consumer (continued)
This drug may reduce blood flow to your hands and feet, causing them to feel cold. Smoking may worsen this effect. Avoid tobacco use and dress warmly.
Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Medications in this class may cause or worsen heart failure. Tell your doctor immediately if you notice any of the following unlikely but very serious side effects: swelling of the feet/ankles, shortness of breath, severe tiredness, unexplained/sudden weight gain.
Tell your doctor immediately if any of these unlikely but serious side effects occur: bluish color of the fingers/toes/nails, hair loss (reversible), mental/mood changes (e.g., confusion, depression, memory problems), pain/cramps in the muscles/joints, numbness/tingling, decreased sexual ability, vision changes, slow/irregular/fast heartbeat, severe dizziness/fainting.
A very serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction may include: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
In the US -
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Read the Visken (pindolol) Side Effects Center for a complete guide to possible side effects
PRECAUTIONS: Before taking pindolol, tell your doctor or pharmacist if you are allergic to it; or to other beta-blockers (e.g., acebutolol); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: asthma, very slow heartbeat (e.g., sinus bradycardia, second- or third-degree atrioventricular block), a certain serious heart condition (cardiogenic shock), uncontrolled severe heart failure.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: severe allergic reactions (e.g., anaphylaxis), breathing problems (e.g., chronic obstructive lung disease-COPD, emphysema, chronic bronchitis), blood circulation problems (e.g., Raynaud's disease, peripheral vascular disease), low blood flow to the heart/brain (e.g., due to coronary artery disease, stroke, transient ischemic attack), diabetes, heart problems (e.g., heart failure, heart attack), kidney disease, liver disease, mental/mood disorders (e.g., depression), a certain muscle problem (myasthenia gravis), overactive thyroid (hyperthyroidism), a certain type of tumor (pheochromocytoma).
This drug may make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Limit alcoholic beverages.
To minimize dizziness and lightheadedness, get up slowly when rising from a seated or lying position.
Before having surgery, tell your doctor or dentist that you are taking this medication.
This drug may infrequently make your blood sugar level rise, causing or worsening diabetes. Tell your doctor immediately if you develop symptoms of high blood sugar such as increased thirst or frequent urination.
If you have diabetes, this medication may mask the fast/pounding heartbeat you would usually feel when your blood sugar level falls too low (hypoglycemia). Other symptoms of a low blood sugar level such as dizziness and sweating are unaffected by this drug.
Kidney function declines as you grow older. This medication is removed by the kidneys and liver. Therefore, elderly people may be at greater risk for side effects such as dizziness while using this drug.
This medication should be used only when clearly needed during pregnancy. It may harm an unborn baby. Discuss the risks and benefits with your doctor.
This drug passes into breast milk and may have undesirable effects on a nursing infant. Consult your doctor before breast-feeding.
Additional Visken Information
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Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Get tips on handling your hypertension.