Vistide (Cidofovir) Drug Overview of Drug Interactions and Missed Dose for Patients and Caregivers at RxList

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May 27, 2012

Vistide

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The human immunodeficiency virus (HIV) is a type of virus called a retrovirus, which infects humans when it comes in contact with tissues such as those that line the vagina, anal area, mouth, or eyes, or through a break in the skin.
HIV infection is generally a slowly progressive disease in which the virus is present throughout the body at all stages of the disease.
Three stages of HIV infection have been described.

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The stage of symptomatic infection, in which the body's immune (or defense) system has...

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Vistide Consumer (continued)

DRUG INTERACTIONS: Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Some products that may interact with this drug include: acyclovir, angiotensin-converting enzyme inhibitors, aminosalicylic acid, barbiturates (e.g., phenobarbital), benzodiazepines (e.g., triazolam), bumetanide, clofibrate, methotrexate, famotidine, furosemide, nonsteroidal anti-inflammatory drugs-NSAIDs (e.g., ibuprofen), theophylline, zidovudine.

If you are taking probenecid and any of the medications listed above, ask your doctor if you should temporarily stop the other medication or decrease its dosage because probenecid may affect how well those medications are removed from your body. This is very important for zidovudine.

Tell your doctor if you have had previous use of foscarnet.

Avoid taking other medications that may damage your kidneys (e.g., amphotericin B, foscarnet, pentamidine, vancomycin, aminoglycosides including tobramycin, nonsteroidal anti-inflammatory drugs-NSAIDs including ibuprofen) within 7 days before and during treatment with this medication. In some cases, serious (possibly fatal) kidney damage may occur. See also Warning section.

Check the labels on all your medicines because they may contain NSAIDs (e.g., ibuprofen, naproxen). Ask your pharmacist about using those products safely.

OVERDOSE: If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US National Poison Hotline at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: change in the amount of urine.

NOTES: Laboratory and/or medical tests (e.g., eye exams) should be performed periodically to monitor your progress or check for side effects. Consult your doctor for more details.

To decrease your risk of spreading HIV disease to others, always use an effective barrier method (e.g., latex or polyurethane condoms/dental dams) during sexual activity. Consult your doctor or pharmacist for more details.

MISSED DOSE: If you miss a dose of cidofovir, contact your doctor or pharmacist immediately to establish a new dosing schedule. If you miss a dose of the probenecid, tell your doctor or pharmacist immediately. You may have to reschedule your cidofovir dose.

STORAGE: Not applicable. This medication is given in a clinic and will not be stored at home.