"The U.S. Food and Drug Administration today expanded the approved use of Xgeva (denosumab) to treat adults and some adolescents with giant cell tumor of the bone (GCTB), a rare and usually non-cancerous tumor.
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- Patient Information:
Details with Side Effects
Important Precautions Regarding VITRASE
Instruct patient that VITRASE is being used to increase the dispersion and absorption of fluids or other injected drugs, as appropriate to the intended use.
What Patients Should Know About Adverse Reactions
Anaphylactic-like reactions, and allergic reactions, such as hives, have been reported rarely in patients receiving hyaluronidases.
Patients Should Inform Their Doctors If Taking Other Medications
You may not receive furosemide, the benzodiazepines, phenytoin, dopamine and/or alpha agonists with VITRASE. These medications have been found to be incompatible with hyaluronidase.
If you are taking salicylates (e.g. aspirin), steroids (e.g., cortisone or estrogens) or antihistamines your doctor may need to prescribe larger amounts of hyaluronidase for equivalent dispersing effect.
Last reviewed on RxList: 5/3/2012
This monograph has been modified to include the generic and brand name in many instances.
Additional Vitrase Information
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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