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Vitrase Side Effects Center
Medical Editor: Melissa Conrad Stöppler, MD
Vitrase (hyaluronidase injection) is an injection indicated to enhance the absorption and dispersion of other injected drugs. The most frequently reported adverse events have been local injection site reactions. Vitrase should not be should not be injected into or around an infected or acutely inflamed area because of the danger of spreading a localized infection.
No adequate and well controlled animal studies have been conducted with Vitrase to determine reproductive effects. No adequate and well controlled studies have been conducted with Vitrase in pregnant women. Vitrase should be used during pregnancy only if clearly needed. It is not known whether Vitrase is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when Vitrase is administered to a nursing woman.
Our Vitrase Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
What is Patient Information in Detail?
Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.
Vitrase in Detail - Patient Information: Side Effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Less serious side effects may include pain, itching, redness, or swelling where the medication was injected.
Read the entire detailed patient monograph for Vitrase (Hyaluronidase Injection)
What is Prescribing information?
The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.
Vitrase FDA Prescribing Information: Side Effects
The following adverse reactions have been identified during post-approval use of hyaluronidase products. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. The most frequently reported adverse reactions have been local injection site reactions.
Hyaluronidase has been reported to enhance the adverse reactions associated with co-administered drug products. Edema has been reported most frequently in association with hypodermoclysis.
Allergic reactions (urticaria, angioedema) have been reported in less than 0.1% of patients receiving hyaluronidase. Anaphylactic-like reactions following retrobulbar block or intravenous injections have occurred, rarely.
Read the entire FDA prescribing information for Vitrase (Hyaluronidase Injection)
Additional Vitrase Information
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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