Vitrasert (Ganciclovir) Drug Information: Description, User Reviews, Drug Side Effects, Interactions

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May 26, 2012

Vitrasert

Human Immunodeficiency Virus »

HIV facts

The human immunodeficiency virus (HIV) is a type of virus called a retrovirus, which infects humans when it comes in contact with tissues such as those that line the vagina, anal area, mouth, or eyes, or through a break in the skin.
HIV infection is generally a slowly progressive disease in which the virus is present throughout the body at all stages of the disease.
Three stages of HIV infection have been described.

The initial stage of infection (primary infection), which occurs within weeks of acquiring the virus, and often is characterized by a flu- or mono-like illness that generally resolves within weeks.
The stage of chronic asymptomatic infection (meaning a long duration of infection without symptoms) lasts an average of eight to 10 years.
The stage of symptomatic infection, in which the body's immune (or defense) system has...

Read the Human Immunodeficiency Virus article »

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Vitrasert

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VITRASERT® (ganciclovir)
STERILE INTRAVITREAL IMPLANT WITH CYTOVENE®
(ganciclovir, 4.5 mg)

FOR INTRAVITREAL IMPLANTATION ONLY

DRUG DESCRIPTION

The Vitrasert Implant contains the antiviral drug ganciclovir. Each Vitrasert Implant contains a minimum of 4.5 mg ganciclovir.

Each Vitrasert Implant contains a ganciclovir tablet which contains the inactive ingredient, magnesium stearate (0.25%). Each tablet is coated with polyvinyl alcohol and ethylene vinyl acetate polymers.

The chemical name of ganciclovir is 9-[[2-hydroxy-1-(hydroxymethyl)ethoxy]methyl]guanine, and has the following structure:

VITRASERT (ganciclovir) Structural Formula Illustration

Ganciclovir is a white to off-white crystalline powder with a molecular formula of C₉H₁₃N₅O₄, and molecular weight of 255.23. Ganciclovir has a solubility of 4.3 mg/mL in water at 25°C.