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Human Immunodeficiency Virus »
The history of the human immunodeficiency virus (HIV) and acquired immunodeficiency syndrome (AIDS) dates back to 1981, when homosexual men with symptoms of a disease that now are considered typical of AIDS were first described in Los Angeles and New York. The men had an unusual type of lung infection (pneumonia) called Pneumocystis carinii (now known as Pneumocystis jiroveci) pneumonia (PCP) and rare skin tumors called Kaposi's sarcomas. The patients were noted to have a severe reduction in a type of cell in the blood (CD4 cells) that is an important part of the immune system. These cells, often referred to as T cells, help the body fight infections. Shortly thereafter, this disease was recognized throughout the United States, Western Europe, and Africa. In 1983, researchers in the United States and France described the virus that causes AIDS, now known as HIV, belonging to t...
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VITRASERT® (ganciclovir)
STERILE INTRAVITREAL IMPLANT WITH CYTOVENE®
(ganciclovir, 4.5 mg)
FOR INTRAVITREAL IMPLANTATION ONLY
The Vitrasert Implant contains the antiviral drug ganciclovir. Each Vitrasert Implant contains a minimum of 4.5 mg ganciclovir.
Each Vitrasert Implant contains a ganciclovir tablet which contains the inactive ingredient, magnesium stearate (0.25%). Each tablet is coated with polyvinyl alcohol and ethylene vinyl acetate polymers.
The chemical name of ganciclovir is 9-[[2-hydroxy-1-(hydroxymethyl)ethoxy]methyl]guanine, and has the following structure:
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Ganciclovir is a white to off-white crystalline powder with a molecular formula of C9H13N5O4, and molecular weight of 255.23. Ganciclovir has a solubility of 4.3 mg/mL in water at 25°C.
Consult your...
Last reviewed on RxList: 12/2/2008
This monograph has been modified to include the generic and brand name in many instances.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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