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Protriptyline hydrochloride tablets are indicated for the treatment of symptoms of mental depression in patients who are under close medical supervision. Its activating properties make it particularly suitable for withdrawn and anergic patients.
DOSAGE AND ADMINISTRATION
Dosage should be initiated at a low level and increased gradually, noting carefully the clinical response and any evidence of intolerance.
Usual Adult Dosage
Fifteen to 40 mg a day divided into 3 or 4 doses. If necessary, dosage may be increased to 60 mg a day. Dosages above this amount are not recommended. Increases should be made in the morning dose.
Adolescent and Elderly Patients
In general, lower dosages are recommended for these patients. Five mg 3 times a day may be given initially, and increased gradually if necessary. In elderly patients, the cardiovascular system must be monitored closely if the daily dose exceeds 20 mg.
When satisfactory improvement has been reached, dosage should be reduced to the smallest amount that will maintain relief of symptoms.
Minor adverse reactions require reduction in dosage. Major adverse reactions or evidence of hypersensitivity require prompt discontinuation of the drug.
The safety and effectiveness of protriptyline in pediatric patients have not been established.
Vivactil (protriptyline hydrochloride tablet) ® Tablets:
|5 mg|| Orange, oval, film-coated tablets in bottles of 100.
Debossed OP 701
|10 mg|| Yellow, oval, film-coated tablets in bottles of 100.
Debossed OP 702
Dispense in a tight container as defined in the USP.
Store at 20°-25°C (68°-77°F) [See USP Controlled Room Temperature].
Duramed Pharmaceuticals, Inc., Subsidiary of Barr Pharmaceuticals, Inc. Pomona, New York 10970. Distributed by: Duramed Pharmaceuticals, Inc. Revised: 10/2008.
Last reviewed on RxList: 8/20/2009
This monograph has been modified to include the generic and brand name in many instances.
Additional Vivactil Information
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