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Vivotif Oral

Vivotif Oral

Vivotif Side Effects Center

Medical Editor: John P. Cunha, DO, FACOEP

Vivotif Oral (typhoid vaccine) is used to help prevent infection (typhoid fever) caused by the bacteria Salmonella typhi. It is recommended for people older than 6 years who are traveling to areas where typhoid fever is common (i.e., Central and South America, Africa, Asia), who are exposed to someone with typhoid infection, or who work with the bacteria in a laboratory. It is a "live" immunization. Common side effects include nausea.

The complete immunization schedule for adults and children above 6 years of age is the ingestion of one Vivotif Oral capsule on each of days 1, 3 and 5. Before receiving Vivotif Oral vaccine, tell the doctor all other vaccines you have recently received. Vivotif Oral may interact with proguanil (Malarone). Other drugs may affect this vaccine. Tell your doctor all prescription and over-the-counter medications you use. During pregnancy, Vivotif Oral vaccine should be used only when prescribed. It is unknown if this medication passes into breast milk. Consult your doctor before breast-feeding.

Our Vivotif Oral (typhoid vaccine) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is Patient Information in Detail?

Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.

Vivotif in Detail - Patient Information: Side Effects

You should not receive a booster dose if you had a life-threatening allergic reaction after taking a typhoid vaccine capsule.

Becoming infected with typhoid is much more dangerous to your health than receiving the vaccine to protect against it. Like any medicine, this vaccine can cause side effects, but the risk of serious side effects is extremely low.

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Less serious side effects include:

  • low fever;
  • headache;
  • nausea, vomiting, diarrhea, stomach pain; or
  • mild skin rash.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Vivotif (Typhoid Vaccine) »

What is Prescribing information?

The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.

Vivotif FDA Prescribing Information: Side Effects
(Adverse Reactions)


Clinical Trials

The following adverse effects were reported as common (in accordance with CIOMS definition of <1/10 and >1/100) and were generally mild - constipation, abdominal cramps, diarrhoea, nausea, vomiting, anorexia, fever, headache and urticarial exanthema.

Postmarketing Data

The following additional adverse effects have been reported very rarely (CIOMS definition: <1/10,000) during postmarketing surveillance.

Skin reactions such as dermatitis, exanthema, pruritus and urticaria, anaphylaxis, asthenia, malaise, tiredness, shivering, paraesthesia, dizziness, arthralgia and myalgia.

Read the entire FDA prescribing information for Vivotif (Typhoid Vaccine) »


Report Problems to the Food and Drug Administration


You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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