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Paget's disease is a chronic condition of bone characterized by disorder of the normal bone remodeling process. Normal bone has a balance of forces that act to lay down new bone and take up old bone. This relationship (referred to as "bone remodeling") is essential for maintaining the normal calcium levels in our blood. In bone affected by Paget's disease, the bone remodeling is disturbed and not synchronized. As a result, the bone that is formed is abnormal, enlarged, not as dense, brittle, and prone to breakage (fracture).
Paget's disease affects older skeletal bone of adults. It's estimated that 1% of adults in the U.S. have Paget's disease. There is also an extremely rare form of Paget's disease in children, referred to as juvenile Paget's disease. Paget's disease is also known as osteitis deformans.
It is not known what causes Paget's disease. Recently, certain...
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Medical Editor: Melissa Conrad Stöppler, MD
Voltaren (diclofenac) is an oral drug that belongs to the nonsteroidal anti-inflammatory drug (NSAID) class. It is used for the treatment of pain, fever, and inflammation by reducing the production of prostaglandins. Voltaren is used primarily for the treatment of inflammation and pain caused by conditions such as rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis. Most common side effects of Voltaren are gastrointestinal disturbances including ulcer formation.
Voltaren should be taken with food to reduce stomach upset. Potential drug interactions include lithium (Eskalith, Lithobid), blood pressure medications, methotrexate (Rheumatrex, Trexall), certain antibiotics, and anticoagulants. Like other NSAIDs, Voltaren is generally avoided during pregnancy because it may affect the cardiovascular system of the fetus. It is not known whether Voltaren is excreted in breast milk.
Our Voltaren Drug Center provides a comprehensive view of available drug information as well as related drugs, user reviews, supplements and disease and conditions
What is Prescribing information?
The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.
Carefully consider the potential benefits and risks of Voltaren® (diclofenac sodium enteric-coated tablets) and other treatment options before deciding to use Voltaren (diclofenac sodium) . Use the lowest effective dose for the shortest duration consistent with individual patient treatment goals (see WARNINGS).
Voltaren (diclofenac sodium) is indicated:
Read the complete drug monograph for Voltaren »
Drug Description - Indications & Dosage - Side Effects & Drug Interactions - Warnings & Precautions - Contraindications - Medication Guide and More
What is Patient information?
Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop taking diclofenac and seek medical attention or call your doctor at once if you have any of these serious side effects:
Read the complete patient information for Voltaren »
Possible Side Effects - Images - What Is - How Should I Take It - What If I Miss a Dose - What Should I Avoid and More
What is Consumer information?
A concise overview of the drug for the patient or caregiver from First DataBank.
OTHER USES: This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care prof...
Read the complete consumer information for Voltaren »
Warnings - Uses - How to Use - Side Effects - Precautions - Drug Interactions and More
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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