"The U.S. Food and Drug Administration yesterday approved Obizur [Antihemophilic Factor (Recombinant), Porcine Sequence] for the treatment of bleeding episodes in adults with acquired hemophilia A (acquired Factor VIII [FVII] deficiency).
The use of Voluven® (hydroxyethyl starch in sodium chloride injection) is contraindicated in the following conditions:
- known hypersensitivity to hydroxyethyl starch [see General WARNINGS and PRECAUTIONS]
- fluid overload (hyperhydration) and especially in cases of pulmonary edema and congestive heart failure
- renal failure with oliguria or anuria not related to hypovolemia
- patients receiving dialysis treatment
- severe hypernatremia or severe hyperchloremia
- intracranial bleeding.
3) Lochbühler H, Galli C, Hagemann H. Hydroxyethyl starch HES 130/0.4 in paediatric surgery: results of an explorative, controlled, multicenter safety study. Crit Care 2003; 7 (Suppl 1):, P107This monograph has been modified to include the generic and brand name in many instances.
Last reviewed on RxList: 2/1/2008
Additional Voluven Information
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