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"The U.S. Food and Drug Administration yesterday approved Ruconest, the first recombinant C1-Esterase Inhibitor product for the treatment of acute attacks in adult and adolescent patients with hereditary angioedema (HAE).

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  • VPRIV should be administered under the supervision of a healthcare professional. VPRIV is a treatment that is given intravenously (by IV) every other week. The infusion typically takes up to 60 minutes.
  • Patients should be advised that VPRIV may cause hypersensitivity reactions or infusion-related reactions. Infusion-related reactions can usually be managed by slowing the infusion rate, treatment with medications such as antihistamines, antipyretics and/or corticosteroids, and/or stopping and resuming treatment with increased infusion time. Pre-treatment with antihistamines and/or corticosteroids may prevent subsequent reactions. Treatment with VPRIV should be carefully re-evaluated in the presence of significant evidence of hypersensitivity to the product [see WARNINGS AND PRECAUTIONS].

Last reviewed on RxList: 10/21/2013
This monograph has been modified to include the generic and brand name in many instances.


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