Vusion

Drug Description
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VUSION™
(0.25% miconazole nitrate, 15% zinc oxide, and 81.35% white petrolatum) Ointment
FOR TOPICAL USE ONLY.
NOT FOR OPHTHALMIC, ORAL, OR INTRAVAGINAL USE.

DRUG DESCRIPTION

VUSION Ointment contains the synthetic antifungal agent, miconazole nitrate (0.25%), zinc oxide (15%) and white petrolatum (81.35%) for topical use.

The chemical name of miconazole nitrate is 1-[2,4-dichloro-β-{(2,4-dichlorobenzyl)oxy} phenethyl] imidazole mononitrate with empirical formula C18H14Cl4N2O•HNO3 and molecular weight of 479.15. The structural formula of miconazole nitrate is as follows:

VUSION™ (0.25% miconazole nitrate, 15% zinc oxide, and 81.35% white petrolatum) Structural Formula Illustration

The zinc oxide has an empirical formula of ZnO and a molecular weight of 81.39.

The white petrolatum, which is obtained from petroleum and is wholly or nearly decolorized, is a purified mixture of semisolid saturated hydrocarbons having the general chemical formula CnH2n+2. The hydrocarbons consist mainly of branched and unbranched chains. White petrolatum contains butylated hydroxytoluene (BHT) as stabilizer.

Each gram of VUSION Ointment contains 2.5 mg of miconazole nitrate USP, 150 mg of zinc oxide USP, 813.5 mg of white petrolatum USP containing butylated hydroxytoluene, trihydroxystearin and Chemoderm® 1001/B fragrance. 1

VUSION Ointment is a smooth, uniform, white ointment.

1 Chemoderm® is a registered trademark of Firmenich Inc.

Last updated on RxList: 11/14/2007

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