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(miconazole nitrate, zinc oxide, and white petrolatum) Ointment, for Topical Use Only


VUSION (miconazole nitrate, 15% zinc oxide, and 81.35% white petrolatum) contains the synthetic antifungal agent, miconazole nitrate (0.25%) USP, zinc oxide (15%) USP, and white petrolatum (81.35%) USP.

The chemical name of miconazole nitrate is 1-[2, 4-dichloro-β-{(2,4-dichlorobenzyl)oxy} phenethyl] imidazole mononitrate with empirical formula C18H14Cl4N2O•HNO3 and molecular weight of 479.15. The structural formula of miconazole nitrate is as follows:

  (miconazole nitrate, zinc oxide, and white petrolatum)  Structural Formula Illustration

The zinc oxide has an empirical formula of ZnO and a molecular weight of 81.39.

The white petrolatum, which is obtained from petroleum and is wholly or nearly decolorized, is a purified mixture of semisolid saturated hydrocarbons having the general chemical formula CnH2n+2. The hydrocarbons consist mainly of branched and unbranched chains. White petrolatum contains butylated hydroxytoluene (BHT) as stabilizer.

Each gram of VUSION (miconazole nitrate, 15% zinc oxide, and 81.35% white petrolatum) contains 2.5 mg of miconazole nitrate USP, 150 mg of zinc oxide USP, and 813.5 mg of white petrolatum USP containing butylated hydroxytoluene, trihydroxystearin, and Chemoderm® 1001/B fragrance.1

VUSION (miconazole nitrate, 15% zinc oxide, and 81.35% white petrolatum) is a smooth, uniform, white ointment.

What are the possible side effects of miconazole and zinc oxide topical (Vusion)?

Get emergency medical help if your child has any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if your child has severe discomfort or redness of treated skin areas.

Common side effects may include dryness or peeling of treated skin.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at...

Read All Potential Side Effects and See Pictures of Vusion »

What are the precautions when taking miconazole nitrate, 15% zinc oxide, and 81.35% white petrolatum (Vusion)?

Before using this product, tell the doctor or pharmacist if your child is allergic to miconazole, zinc oxide, or petrolatum; or to other azole antifungals (e.g., clotrimazole, ketoconazole); or if your child has any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell the doctor or pharmacist your child's medical history.

During pregnancy, this medication should be used only when clearly needed. Pregnant women should use caution when applying this medication on their children. Discuss the risks and benefits with your doctor.

It is not known whether this drug passes into breast milk. Breast-feeding women should use caution when...

Read All Potential Precautions of Vusion »

Last reviewed on RxList: 11/28/2016
This monograph has been modified to include the generic and brand name in many instances.

Vusion - User Reviews

Vusion User Reviews

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