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Vusion

What is diaper rash?

Diaper rash is a generalized term indicating any skin irritation (regardless of cause) that develops in the diaper-covered region. Synonyms include diaper dermatitis (dermatitis = inflammation of the skin), napkin (or "nappy") dermatitis and ammonia dermatitis. While there are a several broad categories of causes of diaper rash, contact irritation is the most common culprit. While diaper rash is generally thought to affect infants and toddlers, any individual wearing a diaper (for example, an incontinent adult) is a candidate to develop this dermatitis.

Is diaper rash a sign of neglectful care?

No, not at all. Parents often incorrectly feel that the rash is a visual representation of poor caretaking skills. However, parents need to understand that the basic causes for this common kind of skin irritation are still under active debate in the field of dermatology and that neglectful parenting is not among the poss...

Vusion

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VUSION®
(miconazole nitrate, zinc oxide, and white petrolatum) Ointment, for Topical Use Only

DRUG DESCRIPTION

VUSION (miconazole nitrate, 15% zinc oxide, and 81.35% white petrolatum) contains the synthetic antifungal agent, miconazole nitrate (0.25%) USP, zinc oxide (15%) USP, and white petrolatum (81.35%) USP.

The chemical name of miconazole nitrate is 1-[2, 4-dichloro-β-{(2,4-dichlorobenzyl)oxy} phenethyl] imidazole mononitrate with empirical formula C18H14Cl4N2O•HNO3 and molecular weight of 479.15. The structural formula of miconazole nitrate is as follows:

VUSION®
  (miconazole nitrate, zinc oxide, and white petrolatum)  Structural Formula Illustration

The zinc oxide has an empirical formula of ZnO and a molecular weight of 81.39.

The white petrolatum, which is obtained from petroleum and is wholly or nearly decolorized, is a purified mixture of semisolid saturated hydrocarbons having the general chemical formula CnH2n+2. The hydrocarbons consist mainly of branched and unbranched chains. White petrolatum contains butylated hydroxytoluene (BHT) as stabilizer.

Each gram of VUSION (miconazole nitrate, 15% zinc oxide, and 81.35% white petrolatum) contains 2.5 mg of miconazole nitrate USP, 150 mg of zinc oxide USP, and 813.5 mg of white petrolatum USP containing butylated hydroxytoluene, trihydroxystearin, and Chemoderm® 1001/B fragrance.1

VUSION (miconazole nitrate, 15% zinc oxide, and 81.35% white petrolatum) is a smooth, uniform, white ointment.

Last reviewed on RxList: 4/27/2010
This monograph has been modified to include the generic and brand name in many instances.

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