"The U.S. Food and Drug Administration today approved Kynamro (mipomersen sodium) injection as an addition to lipid-lowering medications and diet to treat patients with a rare type of high cholesterol called homozygous familial hypercholesterolemi"...
Vytorin Patient Information including If I Miss a Dose
In this Article
- What is ezetimibe and simvastatin (Vytorin)?
- What are the possible side effects of ezetimibe and simvastatin (Vytorin)?
- What is the most important information I should know about ezetimibe and simvastatin (Vytorin)?
- What should I discuss with my healthcare provider before taking ezetimibe and simvastatin (Vytorin)?
- How should I take ezetimibe and simvastatin (Vytorin)?
- What happens if I miss a dose (Vytorin)?
- What happens if I overdose (Vytorin)?
- What should I avoid while taking ezetimibe and simvastatin (Vytorin)?
- What other drugs will affect ezetimibe and simvastatin (Vytorin)?
- Where can I get more information?
What happens if I miss a dose (Vytorin)?
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose (Vytorin)?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
What should I avoid while taking ezetimibe and simvastatin (Vytorin)?
Grapefruit and grapefruit juice may interact with simvastatin and lead to potentially dangerous effects. Do not drink more than 1 quart of grapefruit juice daily.
If you also take cholestyramine (Prevalite, Questran) or colestipol (Colestid), avoid taking them within 2 hours after or 4 hours before you take ezetimibe and simvastatin.
Avoid eating foods that are high in fat or cholesterol. Ezetimibe and simvastatin will not be as effective in lowering your cholesterol if you do not follow a cholesterol-lowering diet plan.
Avoid drinking alcohol. It can raise triglyceride levels and may increase your risk of liver damage.
What other drugs will affect ezetimibe and simvastatin (Vytorin)?
Tell your doctor about all other medications you use, especially:
- colchicine (Colcrys);
- digoxin (Lanoxin);
- a blood thinner such as warfarin (Coumadin, Jantoven);
- fenofibric acid (Fibricor, Trilipix), or fenofibrate (Antara, Fenoglide, Lipofen, Lofibra, Tricor, Triglide);
- antifungal medications such as fluconazole (Diflucan) or voriconazole (Vfend);
- medicines that contain niacin (Advicor, Niaspan, Niacor, Simcor, Slo-Niacin, and others);
- drugs that weaken your immune system, such as steroids, cancer medicine, or medicines used to prevent organ transplant rejection, such as sirolimus (Rapamune), or tacrolimus (Prograf); or
- any other "statin" medication such as atorvastatin (Lipitor, Caduet), fluvastatin (Lescol), lovastatin (Mevacor, Altoprev, Advicor), pravastatin (Pravachol), rosuvastatin (Crestor), or simvastatin (Zocor, Simcor, Juvisync).
This list is not complete and there are many other drugs that can cause serious or life threatening medical problems if you take them together with ezetimibe and simvastatin. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor. Keep a list of all your medicines and show it to any healthcare provider who treats you.
Where can I get more information?
Your pharmacist can provide more information about ezetimibe and simvastatin.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
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