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Pharmacy Editor: Omudhome Ogbru, PharmD
Wellbutrin (bupropion) is an antidepressant in the aminoketone class used for the management of major depression and seasonal affective disorder. A generic formulation is available. The most common side effects of Wellbutrin are agitation, dry mouth, insomnia, headache, nausea, constipation, and tremor. Some patients may experience weight loss. Seizures also occur, especially at higher doses.
The usual dose of Wellbutrin is 150 to 450 mg daily. Wellbutrin should be used cautiously in patients receiving drugs that reduce the threshold for seizures. Monamine oxidase inhibitors (MAOI) should not be combined with Wellbutrin because of the risk of severe reactions. At least 14 days should elapse between discontinuation of an MAOI and initiation of Wellbutrin (bupropion). Wellbutrin may affect the action of Coumadin (warfarin). Norvir (ritonavir) may increase the breakdown and elimination of Wellbutrin (bupropion). There are no adequate studies of Wellbutrin in pregnant women. In one study, there was no difference between Wellbutrin and other antidepressants in the occurrence of birth defects. Wellbutrin is secreted in breast milk.
Our Wellbutrin Drug Center provides a comprehensive view of available drug information as well as related drugs, user reviews, supplements, and diseases and conditions.
What is Prescribing information?
The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.
WELLBUTRIN is indicated for the treatment of major depressive disorder. A physician considering WELLBUTRIN for the management of a patient's first episode of depression should be aware that the drug may cause generalized seizures in a dose-dependent manner with an approximate incidence of 0.4% (4/1,000). This incidence of seizures may exceed that of other marketed antidepressants by as much as 4-fold. This relative risk is only an approximate estimate because no direct comparative studies have been conducted (see WARNINGS).
The efficacy of WELLBUTRIN has be...
Read the complete drug monograph for Wellbutrin »
Drug Description - Indications & Dosage - Side Effects & Drug Interactions - Warnings & Precautions - Contraindications - Medication Guide and More
What is Patient information?
Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any new or worsening symptoms such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself.
Call your doctor at once if you have a serious side effect such as:
Read the complete patient information for Wellbutrin »
Possible Side Effects - Images - What Is - How Should I Take It - What If I Miss a Dose - What Should I Avoid and More
What is Consumer information?
A concise overview of the drug for the patient or caregiver from First DataBank.
OTHER USES: This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional.
Bupropion may also be used to treat a...
Read the complete consumer information for Wellbutrin »
Warnings - Uses - How to Use - Side Effects - Precautions - Drug Interactions and More
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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