"With the possible exception of fluoxetine (multiple brands), the vast majority of antidepressants are ineffective, and some may even be unsafe, for use in children and teens with major depressive disorder (MDD), new research shows.
Wellbutrin XL Patient Information including If I Miss a Dose
In this Article
- What is bupropion (Wellbutrin XL)?
- What are the possible side effects of bupropion?
- What is the most important information I should know about bupropion?
- What should I discuss with my healthcare provider before taking bupropion?
- How should I take bupropion?
- What happens if I miss a dose?
- What happens if I overdose?
- What should I avoid while taking bupropion?
- What other drugs will affect bupropion?
- Where can I get more information?
What happens if I miss a dose?
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of bupropion can be fatal. Overdose symptoms may include muscle stiffness, hallucinations, fast or uneven heartbeat, shallow breathing, or fainting.
What should I avoid while taking bupropion?
Drinking alcohol may increase your risk of seizures. If you drink alcohol regularly, talk with your doctor before changing the amount you drink. Bupropion can cause seizures in people who drink a lot of alcohol and then suddenly quit drinking when they start using the medication.
Bupropion may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.
What other drugs will affect bupropion?
Many drugs can interact with bupropion. Not all possible interactions are listed here. Tell your doctor about all your medications and any you start or stop using during treatment with bupropion, especially:
- medication used to prevent blood clots, such as clopidogrel, ticlopidine, tirofiban;
- heart or blood pressure medication such as atenolol, flecainide, metoprolol, propafenone, propranolol, and others;
- HIV or AIDS medications such as efavirenz or ritonavir; or
- seizure medication such as carbamazepine, phenobarbital, phenytoin.
This list is not complete and many other drugs can interact with bupropion. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Give a list of all your medicines to any healthcare provider who treats you.
You may have a higher risk of seizures if you use certain medications together with bupropion. Tell your doctor about all other medications you use, especially:
- any other antidepressant, or a medicine to treat a psychiatric disorder;
- an antibiotic (amoxicillin, cefdinir, cephalexin, ciprofloxacin, penicillin, and others);
- antihistamines that make you sleepy;
- asthma medications or bronchodilators;
- birth control pills or hormone replacement estrogens;
- bladder or urinary medications (oxybutynin, tolterodine, and others);
- diet pills, a stimulant, or ADHD medication;
- insulin or oral diabetes medication;
- medicine for nausea, vomiting, or motion sickness;
- medications to treat or prevent malaria;
- medicines to treat Parkinson's disease, restless leg syndrome, or pituitary gland tumor (prolactinoma);
- medicines used to prevent organ transplant rejection;
- narcotic pain medication;
- numbing medicine such as lidocaine or Novocain;
- a steroid such as prednisone, and others;
- street drugs such as "speed" or cocaine;
- theophylline; or
- ulcer or irritable bowel medications.
Where can I get more information?
Your pharmacist can provide more information about bupropion.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
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Additional Wellbutrin XL Information
- Wellbutrin XL Drug Interactions Center: bupropion hcl oral
- Wellbutrin XL Side Effects Center
- Wellbutrin XL Overview including Precautions
- Wellbutrin XL FDA Approved Prescribing Information including Dosage
Wellbutrin XL - User Reviews
Wellbutrin XL User Reviews
Now you can gain knowledge and insight about a drug treatment with Patient Discussions.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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