"The U.S. Food and Drug Administration today approved Orbactiv (oritavancin), a new antibacterial drug to treat adults with skin infections.
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(hydrocortisone valerate) Ointment, 0.2%
For Dermatologic Use Only. Not for Ophthalmic Use.
WESTCORT Ointment contains hydrocortisone valerate, 11,2l-dihydroxy-17-[(l-oxopentyl)oxy]-(11β)-pregn-4-ene-3,20-dione, a synthetic corticosteroid for topical dermatologic use. The corticosteroids constitute a class of primarily synthetic steroids used topically as anti-inflammatory and antipruritic agents.
Chemically, hydrocortisone valerate is C26H38O6. It has the following structural formula:
Hydrocortisone valerate has a molecular weight of 446.58. It is a white, crystalline solid, soluble in ethanol and methanol, sparingly soluble in propylene glycol and insoluble in water.
Each gram of WESTCORT Ointment contains 2 mg hydrocortisone valerate in a hydrophilic base composed of white petrolatum, stearyl alcohol, propylene glycol, sorbic acid, sodium lauryl sulfate, carbomer 934, dried sodium phosphate, mineral oil, steareth-2, steareth-100, and water.
What are the possible side effects of hydrocortisone topical?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using hydrocortisone topical and call your doctor at once if you have any of these serious side effects:
- blurred vision, or seeing halos around lights;
- uneven heartbeats;
- sleep problems (insomnia);
- weight gain, puffiness in your face; or
- feeling tired.
Less serious side effects may include:
- skin redness, burning, itching, or peeling;
What are the precautions when taking hydrocortisone valerate ointment (Westcort Ointment)?
Before using hydrocortisone valerate, tell your doctor or pharmacist if you are allergic to it; or to other corticosteroids (e.g., prednisone, triamcinolone); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: poor blood circulation, diabetes, immune system problems.
Do not use if there is an infection or sore in the area to be treated.
Rarely, using corticosteroid medications for a long time or over large areas of skin can make it more difficult for your body to respond to physical stress. Therefore, before having surgery or emergency...
Last reviewed on RxList: 1/13/2009
This monograph has been modified to include the generic and brand name in many instances.
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