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Wigraine

What is Raynaud's phenomenon?

Raynaud's phenomenon (RP) is a condition resulting in a particular series of discolorations of the fingers and/or the toes after exposure to changes in temperature (cold or hot) or emotional events. Skin discoloration occurs because an abnormal spasm of the blood vessels causes a diminished blood supply to the local tissues. Initially, the digit(s) involved turn white because of the diminished blood supply. The digit(s) then turn blue because of prolonged lack of oxygen. Finally, the blood vessels reopen, causing a local "flushing" phenomenon, which turns the digit(s) red. This three-phase color sequence (white to blue to red), most often upon exposure to cold temperature, is characteristic of RP.

Raynaud's phenomenon most frequently affects women, especially in the second, third, or fourth decades of life. People can have Raynauds phenomenon alone or as a part of other rheumatic diseases. When it occurs alone...

Wigraine

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Discontinued Warning IconPlease Note: This Brand Name drug is no longer available in the US.
(Generic versions may still be available.)

DRUG DESCRIPTION

Wigraine (ergotamine and caffeine) ® Tablets:  Each tablet contains the following:

Ergotamine Tartrate, USP      1 mg

Caffeine, USP      100 mg

Each tablet also contains: Lactose, Magnesium Stearate, Microcrystalline Cellulose, Corn Starch, Glycerin, Acacia Powder, Colloidal Silicon Dioxide, and Purified Water as inactive ingredients.

Wigraine (ergotamine and caffeine) ® tablets are uncoated and prepared to insure rapid disintegration (by an exclusive manufacturing process) and facilitate quick absorption. Rapid onset of effect is important for the satisfactory treatment of acute attacks of vascular headaches.

What are the precautions when taking ergotamine and caffeine (Wigraine)?

Before taking this medication, tell your doctor or pharmacist if you are allergic to ergotamine or caffeine; or to other ergot alkaloids (e.g., dihydroergotamine) or to other xanthine drugs (e.g., theophylline); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: blood circulation disease (e.g., peripheral vascular disease such as arteriosclerosis, thrombophlebitis, Raynaud's disease), uncontrolled high blood pressure, nutrient deficiency (malnutrition), heart/blood vessel disease (e.g., coronary artery...

Read All Potential Precautions of Wigraine »

Last reviewed on RxList: 12/8/2004
This monograph has been modified to include the generic and brand name in many instances.

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