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Hepatic: Cholestatic jaundice with, rarely, hepatic necrosis and death. Hepatocellular neoplasms and peliosis hepatis have been reported in association with long-term androgenic-anabolic steroid therapy (see WARNINGS). Reversible changes in liver function tests also occur including increased bromsulphalein (BSP) retention and increases in serum bilirubin, glutamic oxaloacetic transaminase (SGOT), and alkaline phosphatase.
In both sexes: Increased or decreased libido.
Hematologic: Bleeding in patients on concomitant anticoagulant therapy.
Larynx: Deepening of the voice in women.
Metabolic/Endocrine: Decreased glucose tolerance (see PRECAUTIONS), increased serum levels of low-density lipoproteins and decreased levels of high-density lipoproteins (see PRECAUTIONS, Laboratory Tests ), increased creatine and creatinine excretion, increased serum levels of creatinine phosphokinase (CPK).
DRUG ABUSE AND DEPENDENCE
Controlled Substance Class: WINSTROL (anabolic steroids) is classified as a controlled substance under the Anabolic Steroids Control Act of 1990 and has been assigned to Schedule III.
Read the Winstrol (anabolic steroids) Side Effects Center for a complete guide to possible side effects
Anabolic steroids may increase sensitivity to anticoagulants; therefore, dosage of an anticoagulant may have to be decreased in order to maintain the prothrombin time at the desired therapeutic level.
Last reviewed on RxList: 12/8/2004
This monograph has been modified to include the generic and brand name in many instances.
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