"The programmed death (PD-1) inhibitor pembrolizumab (Keytruda, Merck & Co) has been granted approval by the US Food and Drug Administration (FDA) for use in lung cancer, becoming the second immunotherapy available for this tumor type."...
Xalkori Patient Information including How Should I Take
In this Article
- What is crizotinib (Xalkori)?
- What are the possible side effects of crizotinib (Xalkori)?
- What is the most important information I should know about crizotinib (Xalkori)?
- What should I discuss with my healthcare provider before taking crizotinib (Xalkori)?
- How should I take crizotinib (Xalkori)?
- What happens if I miss a dose (Xalkori)?
- What happens if I overdose (Xalkori)?
- What should I avoid while taking crizotinib (Xalkori)?
- What other drugs will affect crizotinib (Xalkori)?
- Where can I get more information?
What should I discuss with my healthcare provider before taking crizotinib (Xalkori)?
You should not use crizotinib if you are allergic to it.
To make sure you can safely use crizotinib, tell your doctor if you have any of these other conditions:
- liver or kidney disease;
- a heart rhythm disorder;
- a personal or family history of Long QT syndrome; or
- an electrolyte imbalance (such as low levels of potassium or magnesium in your blood).
FDA pregnancy category D. Do not use crizotinib if you are pregnant. It could harm the unborn baby. Use effective birth control while you are using this medication and for at least 3 months after your treatment ends.
If a man fathers a child while using this medicine, the baby may have birth defects. Use a condom to prevent pregnancy while you are using this medication and for at least 3 months after your treatment ends.
It is not known whether crizotinib passes into breast milk or if it could harm a nursing baby. You should not breast-feed while you are using crizotinib.
How should I take crizotinib (Xalkori)?
Before you start treatment, your doctor may perform tests to make sure crizotinib is the best treatment for your type of lung cancer.
Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.
Crizotinib is usually taken twice per day. Follow your doctor's instructions.
You may take crizotinib with or without food.
Do not crush, chew, dissolve, or open a crizotinib capsule. Swallow it whole.
To be sure this medicine is helping your condition and is not causing harmful effects, your blood cells and liver function may need to be tested often. Your heart function may need to be tested with an electrocardiogram (ECG or EKG). Your cancer treatments may be delayed based on the results of these tests. Do not miss any follow-up visits to your doctor.
Do not stop taking this medication without first talking to your doctor.
Store in the original container at room temperature away from moisture and heat. Keep the bottle tightly closed when not in use.
Additional Xalkori Information
- Xalkori Drug Interactions Center: crizotinib oral
- Xalkori Side Effects Center
- Xalkori FDA Approved Prescribing Information including Dosage
Report Problems to the Food and Drug Administration
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