"Nov. 6, 2012 -- The FDA has approved Pfizer's Xeljanz (tofacitinib), a first-of-its-kind treatment for rheumatoid arthritis.
Xeljanz is approved for use by patients not helped by methotrexate, the usual first treatment for RA. It's a "...
Signs, Symptoms, and Laboratory Findings of Acute Overdosage in Humans
There is no experience with overdose of XELJANZ.
Treatment or Management of Overdose
Pharmacokinetic data up to and including a single dose of 100 mg in healthy volunteers indicate that more than 95% of the administered dose is expected to be eliminated within 24 hours.
There is no specific antidote for overdose with XELJANZ. In case of an overdose, it is recommended that the patient be monitored for signs and symptoms of adverse reactions. Patients who develop adverse reactions should receive appropriate treatment.
Last reviewed on RxList: 3/5/2014
This monograph has been modified to include the generic and brand name in many instances.
Additional Xeljanz Information
- Xeljanz Drug Interactions Center: tofacitinib oral
- Xeljanz Side Effects Center
- Xeljanz FDA Approved Prescribing Information including Dosage
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