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Xenazine

Introduction to Huntington's disease

In 1872, the American physician George Huntington wrote about an illness that he called "an heirloom from generations away back in the dim past." He was not the first to describe the disorder, which has been traced back to the Middle Ages at least. One of its earliest names was chorea,* which, as in "choreography," is the Greek word for dance. The term chorea describes how people affected with the disorder writhe, twist, and turn in a constant, uncontrollable dance--like motion. Later, other descriptive names evolved. "Hereditary chorea" emphasizes how the disease is passed from parent to child. "Chronic progressive chorea" stresses how symptoms of the disease worsen over time. Today, physicians commonly use the simple term Huntington's disease (HD) to describe this highly complex disorder that causes untold suffering for thousands of families.

More than 15,000 Americans have HD. At least 150,000 others have a 50 percent ri...

Xenazine

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Xenazine Patient Information including If I Miss a Dose

What happens if I miss a dose (Xenazine)?

Take the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to take the medicine and skip the missed dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose (Xenazine)?

Seek emergency medical attention if you think you have used too much of this medicine.

Overdose symptoms may include nausea and vomiting, diarrhea, sweating, confusion, hallucinations, tremors, and restless muscle movements in your eyes, tongue, jaw, or neck.

What should I avoid while taking tetrabenazine (Xenazine)?

Tetrabenazine can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Avoid drinking alcohol. It can increase some of the side effects of tetrabenazine.

What other drugs will affect tetrabenazine (Xenazine)?

Tell your doctor about all other medications you use, especially:

  • arsenic trioxide (Trisenox);
  • droperidol (Inapsine);
  • celecoxib (Celebrex);
  • cimetidine (Tagamet);
  • darifenacin (Enablex);
  • ropinirole (Requip);
  • terbinafine (Lamisil);
  • ADHD medications (Adderall, Ritalin, Strattera);
  • an antibiotic such as clarithromycin (Biaxin), erythromycin (E.E.S., EryPed, Ery-Tab, Erythrocin), levofloxacin (Levaquin), moxifloxacin (Avelox), or pentamidine (NebuPent, Pentam);
  • an antidepressant such as amitriptyline (Elavil), amoxapine (Asendin), bupropion (Wellbutrin, Zyban), clomipramine (Anafranil), desipramine (Norpramin), duloxetine (Cymbalta), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem), imipramine (Tofranil), paroxetine (Paxil), sertraline (Zoloft);
  • anti-malaria medication;
  • cancer medications such as gefitinib (Iressa), imatinib (Gleevec), or nilotinib (Tasigna);
  • a heart rhythm medication;
  • HIV or AIDS medicine such as delavirdine (Rescriptor) or ritonavir (Norvir);
  • medicine to treat or prevent nausea and vomiting, such as dolasetron (Anzemet), metoclopramide (Reglan), ondansetron (Zofran), or promethazine (Phenergan, Promacot);
  • medicine to treat psychiatric disorders, such as aripiprazole (Abilify), chlorpromazine (Thorazine), clozapine (FazaClo, Clozaril), haloperidol (Haldol), perphenazine (Trilafon), thioridazine (Mellaril), ziprasidone (Geodon), and others;
  • migraine headache medicine such as sumatriptan (Imitrex) or zolmitriptan (Zomig); or
  • a narcotic such as levomethadyl (Orlaam), methadone (Methadose, Diskets, Dolophine) or propoxyphene (Darvon, Darvocet).

This list is not complete and there may be other drugs that can interact with tetrabenazine. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.

Where can I get more information?

Your pharmacist can provide more information about tetrabenazine.


Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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