"By Roxanne Nelson
Another study showing an increased risk for cancer with drinking alcohol, even with just one or two drinks a day, has prompted renewed warnings on the health risks associated with alcohol consumption.
Xgeva Patient Information including How Should I Take
In this Article
- What is denosumab (Xgeva) (Xgeva)?
- What are the possible side effects of Xgeva (Xgeva)?
- What is the most important information I should know about Xgeva (Xgeva)?
- What should I discuss with my healthcare provider before receiving Xgeva (Xgeva)?
- How is Xgeva given (Xgeva)?
- What happens if I miss a dose (Xgeva)?
- What happens if I overdose (Xgeva)?
- What should I avoid while receiving Xgeva (Xgeva)?
- What other drugs will affect Xgeva (Xgeva)?
- Where can I get more information?
What should I discuss with my healthcare provider before receiving Xgeva (Xgeva)?
You should not receive denosumab if you are allergic to it, or if you have low levels of calcium in your blood (hypocalcemia).
To make sure you can safely use Xgeva, tell your doctor if you have kidney disease or if you are on dialysis.
FDA pregnancy category D. Do not use denosumab if you are pregnant. It could harm the unborn baby. Use effective birth control, and tell your doctor if you become pregnant during treatment.
If you are pregnant, your name may be listed on a pregnancy registry. This is to track the outcome of the pregnancy and to evaluate any effects of denosumab on the baby.
It is not known whether denosumab passes into breast milk or if it could harm a nursing baby. However, this medication may slow the production of breast milk. You should not breast-feed while receiving denosumab.
Some people using denosumab have developed bone loss in the jaw, also called osteonecrosis of the jaw. Symptoms may include jaw pain, swelling, numbness, loose teeth, gum infection, or slow healing after injury or surgery involving the gums. You may be more likely to develop osteonecrosis of the jaw if you have cancer or have been treated with chemotherapy, radiation, or steroids. Other conditions associated with osteonecrosis of the jaw include blood clotting disorders, anemia (low red blood cells), and a pre-existing dental problem.
How is Xgeva given (Xgeva)?
Denosumab is injected under the skin of your stomach, upper thigh, or upper arm. A healthcare provider will give you this injection.
Xgeva is usually given once every 4 weeks. Follow your doctor's instructions.
Your doctor may have you take extra calcium and vitamin D while you are being treated with denosumab. Take only the amount of calcium and vitamin D that your doctor has prescribed.
Pay special attention to your dental hygiene. Brush and floss your teeth regularly while receiving this medication. You may need to have a dental exam before you begin treatment with Xgeva. Follow your doctor's instructions.
If you need to have any dental work (especially surgery), tell the dentist ahead of time that you are receiving denosumab. You may need to stop using the medicine for a short time.
If you keep your medication at home, store it in the original container in a refrigerator. Protect from light and do not freeze.
You may take the medicine out of the refrigerator and allow it to reach room temperature before giving the injection. Do not heat the medicine before using.
After you have taken Xgeva out of the refrigerator, you may keep it at room temperature and use it within 14 days. Store in the original container away from heat and light.
Do not shake the medication bottle or you may ruin the medicine. Prepare your dose in a syringe only when you are ready to give yourself an injection. Do not use the medication if it looks cloudy or has particles in it. Call your doctor for a new prescription.
Each single use vial (bottle) of this medicine is for one use only. Throw away after one use, even if there is still some medicine left in it after injecting your dose.
Additional Xgeva Information
- Xgeva Drug Interactions Center: denosumab subq
- Xgeva Side Effects Center
- Xgeva Overview including Precautions
- Xgeva FDA Approved Prescribing Information including Dosage
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