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Xifaxan
E. coli 0157:H7 Facts
- E. coli 0157:H7 is a gram-negative bacterium that can produce a bloody diarrhea due to toxins it secretes when it infects human intestinal tracts.
- The symptoms of E. coli 0157:H7 infection may include a low fever, nausea, vomiting, stomach cramps, and bloody diarrhea.
- E. coli 0157:H7 is notorious because it can cause additional complications in children and the elderly; renal failure, anemia, and dehydration especially for children (termed HUS or Hemolytic-uremic syndrome) and spontaneous bleeding, organ failures, and mental changes in the elderly (termed TTP or thrombotic thrombocytopenic purpura). Some of these patients develop disabilities or die.
- Diagnosis is definitively made when E. coli 0157:H7 is isolated, usually from the patient's stool, and identified as serotype 0157 by immunologic tests.
- Most E. coli 0157:H7 infections resolve s...
Xifaxan
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Xifaxan Drug Center
Pharmacy Editor: Charles Patrick Davis, MD, PhD
Xifaxan is a semi-synthetic antibiotic indicated for the treatment of patients ( ≥ 12 years of age) with travelers' diarrhea caused by noninvasive strains of Escherichia coli and for hepatic encephalopathy. Currently, Xifaxan has no FDA approved generic equivalent. Side effects may include nausea, vomiting, bloating, gas, abdominal pain, and people may feel they need to urgently defecate.
Xifaxan (rifaximin) tablets for oral administration are film-coated and contain 200 or 550 mg of rifaximin. Usual dosage is 200 mg three times a day for three days for diarrhea and 550mg twice a day for 3 days for hepatic encephalopathy. Serious side effects include C. difficile diarrhea and continued diarrhea due to organisms resistant to the drug. Caution is suggested when treating severe hepatic encephalopathy as systemic drug toxicity may develop. There are no adequate and well controlled studies of Xifaxan use in pregnancy; the drug should be used during pregnancy only if the potential benefit outweighs the potential risk to the fetus. It is not known if the drug is present in breast milk. The safety and effectiveness of Xifaxan in pediatric patients with travelers' diarrhea less than 12 years of age have not been established.
Our Xifaxan Drug Center provides a comprehensive view of available drug information as well as related drugs, user reviews, supplements, and diseases, and conditions.
What is Prescribing information?
The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.
Xifaxan Prescribing Information: Indications & Dosage
To reduce the development of drug-resistant bacteria and maintain the effectiveness of XIFAXAN (rifaximin) and other antibacterial drugs, XIFAXAN (rifaximin) when used to treat infection should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria. When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy. In the absence of such data, local epidemiology and susceptibility patterns may contribute to the empiric selection of thera...
Read the complete drug monograph for Xifaxan »
What is Xifaxan Prescribing Information?
Drug Description - Indications & Dosage - Side Effects & Drug Interactions - Warnings & Precautions - Contraindications - Medication Guide and More
What is Patient information?
Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.
Xifaxan Patient Information: Side Effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using rifaximin and call your doctor at once if you have a fever or diarrhea that is watery or bloody.
Less serious side effects may be more likely to occur, such as:
- bloating, gas, stomach pain;
- feeling like you need to empty your bowel urgently;
- feeling like your bowel is not completely empty;
- nausea, vomiting, constipation;
- headache;
- fever;/...
Read the complete patient information for Xifaxan »
What is Xifaxan Patient Information?
Possible Side Effects - Images - What Is - How Should I Take It - What If I Miss a Dose - What Should I Avoid and More
What is Consumer information?
A concise overview of the drug for the patient or caregiver from First DataBank.
Xifaxan Consumer Information: Uses
This medication is used to treat diarrhea caused by the common bacteria known as E. coli ("traveler's diarrhea"). Rifaximin should not be used if you have a fever or bloody diarrhea. This medication stays in the digestive system and is not absorbed into the blood. It works by stopping the growth of bacteria.
This antibiotic treats only bacterial infections. It will not work for viral infections (e.g., common cold, flu). Unnecessary use or overuse of any antibiotic can lead to its decreased effectiveness.
Rifaximin is also used to prevent a brain problem caused by liver disease (hepatic e...
Read the complete consumer information for Xifaxan »
What is Xifaxan Consumer Information?
Warnings - Uses - How to Use - Side Effects - Precautions - Drug Interactions and More
Next: Drug Description
Additional Xifaxan Information
Xifaxan - User Reviews
Xifaxan User Reviews
Now you can gain knowledge and insight about a drug treatment with Patient Discussions.
Here is a collection of user reviews for the medication Xifaxan sorted by most helpful.
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