Xifaxan (Rifaximin) Drug Overview of Side Effects and Precautions for Patients and Caregivers at RxList

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May 27, 2012

Xifaxan

E. Coli (0157:H7) »

E. coli 0157:H7 Facts

E. coli 0157:H7 is a gram-negative bacterium that can produce a bloody diarrhea due to toxins it secretes when it infects human intestinal tracts.
The symptoms of E. coli 0157:H7 infection may include a low fever, nausea, vomiting, stomach cramps, and bloody diarrhea.
E. coli 0157:H7 is notorious because it can cause additional complications in children and the elderly; renal failure, anemia, and dehydration especially for children (termed HUS or Hemolytic-uremic syndrome) and spontaneous bleeding, organ failures, and mental changes in the elderly (termed TTP or thrombotic thrombocytopenic purpura). Some of these patients develop disabilities or die.
Diagnosis is definitively made when E. coli 0157:H7 is isolated, usually from the patient's stool, and identified as serotype 0157 by immunologic tests.
Most E. coli 0157:H7 infections resolve s...

Read the E. Coli (0157:H7) article »

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Xifaxan Consumer (continued)

SIDE EFFECTS: Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

This medication may rarely cause a severe intestinal condition (Clostridium difficile-associated diarrhea) due to a type of resistant bacteria. This condition may occur during treatment or weeks to months after treatment has stopped. Do not use anti-diarrhea products or narcotic pain medications if you have any of the following symptoms because these products may make them worse. Tell your doctor immediately if you develop: persistent diarrhea, abdominal or stomach pain/cramping, blood/mucus in your stool.

A very serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction may include: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

PRECAUTIONS: Before taking rifaximin, tell your doctor or pharmacist if you are allergic to it; or to other rifamycins (rifampin, rifabutin); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history.

This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor.

It is not known whether this drug passes into breast milk. Consult your doctor before breast-feeding.