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Xigris

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Xigris Drug Center

What is Prescribing information?

The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.

Xigris Prescribing Information: Indications & Dosage

Xigris (drotrecogin alfa) ® is indicated for the reduction of mortality in adult patients with severe sepsis (sepsis associated with acute organ dysfunction) who have a high risk of death (e.g., as determined by APACHE II score ≥ 25) [see Clinical Studies].

Limitations of use:

Xigris (drotrecogin alfa) is not indicated in adult patients with severe sepsis and a lower risk of death (e.g., APACHE II score < 25) [see Clinical Studies].

Xigris (drotrecogin alfa) is not indicated in pediatric patients [see Clinical Studi...

Read the complete drug monograph for Xigris »

What is Patient information?

Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.

Xigris Patient Information: Side Effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Tell your caregivers at once if you have any of these serious side effects:

  • blood in your urine or stools;
  • coughing up blood or vomit that looks like coffee grounds;
  • bleeding from any incision or injection in your skin; or
  • any bleeding that won't stop.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bo...

Read the complete patient information for Xigris »

Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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