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Xtandi

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Xtandi

XTANDI®
(enzalutamide) Soft Gelatin Capsules for Oral Administration

DRUG DESCRIPTION

Enzalutamide is an androgen receptor inhibitor. The chemical name is 4-{3-[4-cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-sulfanylideneimidazolidin-1-yl}-2-fluoro-Nmethylbenzamide.

The molecular weight is 464.44 and molecular formula is C21H16F4N4O2S. The structural formula is:

XTANDI® (enzalutamide) Structural Formula Illustration

Enzalutamide is a white crystalline non-hygroscopic solid. It is practically insoluble in water.

XTANDI is provided as liquid-filled soft gelatin capsules for oral administration. Each capsule contains 40 mg of enzalutamide as a solution in caprylocaproyl polyoxylglycerides. The inactive ingredients are caprylocaproyl polyoxylglycerides, butylated hydroxyanisole, butylated hydroxytoluene, gelatin, sorbitol sorbitan solution, glycerin, purified water, titanium dioxide, and black iron oxide.

What are the possible side effects of enzalutamide (Xtandi)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using enzalutamide and call your doctor at once if you have:

  • seizure (black-out or convulsions);
  • severe low back pain, trouble walking or standing up;
  • pain or weakness in your lower body, severe and worsening numbness or tingly feeling;
  • sudden loss of bladder or bowel control;
  • fever, cough with yellow or green mucus, stabbing chest pain, wheezing, feeling short of...

Read All Potential Side Effects and See Pictures of Xtandi »

Last reviewed on RxList: 9/17/2014
This monograph has been modified to include the generic and brand name in many instances.

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Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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