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Yellow Fever (cont.)

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What is the incubation period for yellow fever?

The period of time from contracting the infection to the development of symptoms (incubation period) is generally between three to six days.

What are yellow fever symptoms and signs?

After infection with the yellow fever virus, many individuals will experience no clinically apparent manifestations of the disease (asymptomatic), while others will go on to develop a mild, self-limiting flu-like illness characterized by the following symptoms and signs:

  • fever,
  • chills,
  • generalized muscle aches,
  • back pain,
  • headache,
  • malaise,
  • weakness,
  • lack of appetite,
  • nausea,
  • vomiting.

Most patients with this initial acute phase of the disease improve after approximately three to four days. However, 15% of patients may enter a second phase of the disease which typically appears after a short remission of symptoms (about 24 hours) from the initial phase of the illness. This toxic phase of the disease is more severe, at which time the high fever returns and more organ systems become involved. In addition to the above symptoms, the following symptoms and signs may also develop:

  • abdominal pain,
  • jaundice,
  • bleeding from the gums, nose, eyes, and/or stomach,
  • blood in the stool (black stool) and blood in the vomit (black vomit),
  • easy bruising of the skin,
  • kidney failure,
  • confusion,
  • seizures,
  • coma,
  • death.
Medically Reviewed by a Doctor on 1/16/2014


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