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Yohimbine readily penetrates the CNS and produces a complex pattern of responses in lower doses than required to produce peripheral alpha-adrenergic blockade. These include, anti-diuresis, a general picture of central excitation including elevation of blood pressure and heart rate, increased motor activity, irritability, and tremor. Sweating, nausea and vomiting are common after parenteral administration of the drug.1,2 Also dizziness, headache, skin flushing reported when used orally.1,3
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No information provided.
1. A. Morales et al., New England Journal of Medicine: 1221. November 12, 1981.
2. Goodman, Gilman - The Pharmacological basis of Therapeutics 6th ed., p. 176- 188, McMillan
3. Weekly Urological Clinical letter, 27:2, July 4, 1983
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Last reviewed on RxList: 5/12/2008
This monograph has been modified to include the generic and brand name in many instances.
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