Zaditor (Ketotifen Fumarate) Drug Information: Description, User Reviews, Drug Side Effects, Interactions

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February 8, 2012

Zaditor

Allergy Drugs: Prescription and OTC »

Allergy medications overview

The arsenal of allergy drugs includes dozens of medications that relieve allergy symptoms when confronted with a trigger known as an allergen. That trigger could be something from a plant, such as pollen, or something from an animal (pet dander, dust mites, cockroaches). Other allergy triggers include certain fragrances or chemical substances.

What causes a person's allergic reaction is highly individual. But the reactions are often universal: swelling and inflammation, especially around the eyes, nose, and throat, usually accompanied by itching.

Some allergy medications work against the effects of histamines, which are released during an allergic reaction. Other medications reduce swelling, affect the immune system, or affect release of other substances associated with allergic reactions.

Many allergy drugs are available without a prescription.

For what conditions are allergy medicatio...

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Zaditor

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ZADITOR®
(ketotifen fumarate) Ophthalmic Solution, 0.025%
Now available Over-The-Counter (OTC); No prescription needed.

DRUG DESCRIPTION

Zaditor® (ketotifen fumarate) is an antihistamine eye drop to relieve itchy eyes due to allergens.

ZADITOR® (ketotifen fumarate) is a sterile ophthalmic solution containing ketotifen for topical administration to the eyes. Ketotifen fumarate is a finely crystalline powder with an empirical formula of C₂₃H₂₃NO₅S and a molecular weight of 425.50.

Established Name: Ketotifen Fumarate Ophthalmic Solution

Chemical Name: 4-(1-Methyl-4-piperidylidene)-4H-benzo[4,5]cyclohepta[1,2-b] thiophen-10(9H)-one hydrogen fumarate

Each mL of ZADITOR (ketotifen fumarate) &reade; contains:

Active: 0.345 mg ketotifen fumarate equivalent to 0.25 mg ketotifen.

Inactives: glycerol, sodium hydroxide/hydrochloric acid (to adjust pH) and purified water.

Preservative: benzalkonium chloride 0.01%. It has a pH of 4.4 to 5.8 and an osmolality of 210-300 mOsm/kg.

What are the possible side effects of ketotifen ophthalmic (Alaway, Zaditor)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using ketotifen ophthalmic and call your doctor at once if you have any of these serious side effects:

redness, drainage, eyelid swelling, or other signs of infection;
eye pain;
vision changes; or
severe itching of the eyes worse than before using the medication.

Less serious side effects may...

Read All Potential Side Effects and See Pictures of Zaditor »

What are the precautions when taking ketotifen fumarate (Zaditor)?

Before using ketotifen, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients (such as the preservative benzalkonium chloride in the multi-dose container), which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: eye problems (e.g., glaucoma).

After you apply this drug, your vision may become temporarily blurred. Do not drive, use machinery, or do any activity that requires clear vision until you are sure you can perform such activities safely.

Do not use this medication in children younger than 3 years unless directed by the doctor.

During...

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Last reviewed on RxList: 5/15/2008
This monograph has been modified to include the generic and brand name in many instances.