Zanaflex (Tizanidine) Drug Center: Guide to Drug Information for Professionals, Patients and Caregivers at RxList

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May 27, 2012

Zanaflex

Chronic Pain »

Introduction to Chronic Pain

You know it at once. It may be the fiery sensation of a burn moments after your finger touches the stove. Or it's a dull ache above your brow after a day of stress and tension. Or you may recognize it as a sharp pierce in your back after you lift something heavy.

It is pain. In its most benign form, it warns us that something isn't quite right, that we should take medicine or see a doctor. At its worst, however, pain robs us of our productivity, our well-being, and, for many of us suffering from extended illness, our very lives. Pain is a complex perception that differs enormously among individual patients, even those who appear to have identical injuries or illnesses.

In 1931, the French medical missionary Dr. Albert Schweitzer wrote, "Pain is a more terrible lord of mankind than even death itself." Today, pain has become the universal disorder, a serious and costly public health issue, and a challenge for famil...

Read the Chronic Pain article »

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Zanaflex Drug Center

Medical Editor: Melissa Conrad Stöppler, MD

Prescribing Information

For Patients

Zanaflex (tizanidine) is a muscle relaxant drug that is used to treat muscle tightness and cramping (spasm) caused by conditions such as multiple sclerosis or spinal injury. Side effects may include constipation, dry mouth, drowsiness, dizziness, weakness, and fatigue. Zanaflex may cause withdrawal reactions, especially if it has been used regularly for a long time or in high doses.

Zanaflex should not be used with ciprofloxacin or fluvoxamine because very serious interactions may occur, and interactions with other drugs are also possible. Zanaflex should be used only when clearly needed during pregnancy. It is not known whether this drug is excreted into human breast milk.

Our Zanaflex Drug Center provides a comprehensive view of available drug information as well as related drugs, user reviews, supplements and disease and conditions.

What is Prescribing information?

The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.

Zanaflex Prescribing Information: Indications & Dosage

Zanaflex (tizanidine hydrochloride) structural formula illustration

Zanaflex Capsules™ (tizanidine) are supplied as 2, 4, and 6 mg capsules and Zanaflex (tizanidine) ® tablets are supplied as 2 and 4 mg tablets for oral administration. Zanaflex (tizanidine) Capsules™ are composed of the active ingredient, tizanidine hydrochloride (2.29 mg equivalent to 2 mg tizanidine base, 4.58 mg equivalent to 4 mg tizanidine base, and 6.87 mg equivalent to 6 mg tizanidine base), and the inactive ingredients, hydroxypropyl methyl cellulose, silicon dioxide, sugar spheres, titanium dioxide, gelatin, and colorants.

Tizanidine is a short-acting drug for the management of spasticity. Because of the short duration of effect, treatment with tizanidine should be reserved for those daily activities and times when relief of spasticity is most important (see DOSING AND ADMINISTRATION).

Read the complete drug monograph for Zanaflex »

What is Zanaflex Prescribing Information?

Drug Description - Indications & Dosage - Side Effects & Drug Interactions - Warnings & Precautions - Contraindications - Medication Guide and More

What is Patient information?

Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.

Zanaflex Patient Information: Side Effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

feeling light-headed, fainting, slow heart rate;
hallucinations, confusion, unusual thoughts or behavior;
nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); or
burning or pain when you urinate.

Less serious side e...

Read the complete patient information for Zanaflex »

What is Zanaflex Patient Information?

Possible Side Effects - Images - What Is - How Should I Take It - What If I Miss a Dose - What Should I Avoid and More

What is Consumer information?

A concise overview of the drug for the patient or caregiver from First DataBank.

Zanaflex Consumer Information: Uses

This medication is used to treat muscle tightness and cramping (spasm) caused by conditions such as multiple sclerosis or spinal injury. Decreasing spasms can reduce pain and improve your ability to move around. Tizanidine is a short-acting muscle relaxant that works by blocking certain nerve signals from the spine to the brain (alpha adrenergic agonist).

HOW TO USE: Take this medication by mouth as directed. When you start this medication, your dosage will probably need to be increased slowly by your doctor to reduce side effects, especially dizzin...

Read the complete consumer information for Zanaflex »