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Introduction to Chronic Pain

You know it at once. It may be the fiery sensation of a burn moments after your finger touches the stove. Or it's a dull ache above your brow after a day of stress and tension. Or you may recognize it as a sharp pierce in your back after you lift something heavy.

It is pain. In its most benign form, it warns us that something isn't quite right, that we should take medicine or see a doctor. At its worst, however, pain robs us of our productivity, our well-being, and, for many of us suffering from extended illness, our very lives. Pain is a complex perception that differs enormously among individual patients, even those who appear to have identical injuries or illnesses.

In 1931, the French medical missionary Dr. Albert Schweitzer wrote, "Pain is a more terrible lord of mankind than even death itself." Today, pain has become the universal disorder, a serious and costly public health issue, and a challenge for famil...

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Zanaflex

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Zanaflex Patient Information Including Side Effects

Brand Names: Zanaflex

Generic Name: tizanidine (Pronunciation: tye ZAN i deen)

What is tizanidine (Zanaflex)?

Tizanidine is a short-acting muscle relaxer. It works by blocking nerve impulses (pain sensations) that are sent to your brain.

Tizanidine is used to treat spasticity by temporarily relaxing muscle tone.

Tizanidine may also be used for purposes other than those listed in this medication guide.

Tizanidine 2 mg-EON

round, white, imprinted with E 34

Tizanidine 2 mg-PAR

oval, white, imprinted with R179

Tizanidine 2 mg-TEV

round, white, imprinted with 93 5163

Tizanidine 4 mg-EON

round, white, imprinted with E 44

Tizanidine 4 mg-TEV

round, white, imprinted with 93 5160

Zanaflex 4 mg

round, white, imprinted with A 594

What are the possible side effects of tizanidine (Zanaflex)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

  • feeling light-headed, fainting, slow heart rate;
  • hallucinations, confusion, unusual thoughts or behavior;
  • nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); or
  • burning or pain when you urinate.

Less serious side effects may be more likely to occur, such as:

  • drowsiness or dizziness;
  • feeling anxious or nervous;
  • numbness or tingling;
  • stomach pain, diarrhea, constipation, vomiting;
  • fever;
  • dry mouth;
  • muscle weakness, back pain;
  • increased muscle tone or spasms; or
  • sweating or skin rash.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about tizanidine (Zanaflex)?

Tizanidine is a short-acting medication that should be taken only for daily activities that require relief from muscle spasticity.

Do not take tizanidine if you are also taking the antidepressant fluvoxamine (Luvox), or the antibiotic ciprofloxacin (Cipro).

Do not use tizanidine at a time when muscle tone is needed to assure safe balance and movement for certain activities. In some situations, it may endanger your physical safety to be in a state of reduced muscle tone.

Switching between tizanidine tablets and capsules, or changing the way you take it with regard to eating, can cause an increase in side effects or a decrease in therapeutic effect. Follow your doctor's instructions carefully. After making any changes in how you take tizanidine, contact your doctor if you notice any change in how well the medicine works or if it causes increased side effects.

Do not take more than three doses (36 mg) of tizanidine in a 24-hour period. Too much of this medication can damage your liver.

Cold or allergy medicine, narcotic pain medicine, sleeping pills, other muscle relaxers, and medicine for seizures, depression or anxiety can add to sleepiness caused by tizanidine. Tell your doctor if you need to use any of these other medicines together with tizanidine.

Avoid drinking alcohol. It can increase some of the side effects of tizanidine.

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Zanaflex - User Reviews

Zanaflex User Reviews

Now you can gain knowledge and insight about a drug treatment with Patient Discussions.

Here is a collection of user reviews for the medication Zanaflex sorted by most helpful. Patient Discussions FAQs

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Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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