Zarontin
Seizure (Epilepsy) on MedicineNet »
"Introduction
Few experiences match the drama of a convulsive seizure. A person having a severe seizure may cry out, fall to the floor unconscious, twitch or move uncontrollably, drool, or even lose bladder control. Within minutes, the"...
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Zarontin
OVERDOSE
Acute overdoses may produce nausea, vomiting, and CNS depression including coma with respiratory depression. A relationship between ethosuximide toxicity and its plasma levels has not been established.
The therapeutic range of serum levels is 40 mcg/mL to 100 mcg/mL, although levels as high as 150 mcg/mL have been reported without signs of toxicity.
Treatment
Treatment should include emesis (unless the patient is or could rapidly become obtunded, comatose, or convulsing) or gastric lavage, activated charcoal, cathartics, and general supportive measures. Hemodialysis may be useful to treat ethosuximide overdose. Forced diuresis and exchange transfusions are ineffective.
CONTRAINDICATION
Ethosuximide should not be used in patients with a history of hypersensitivity to succinimides.
Last reviewed on RxList: 5/21/2012
This monograph has been modified to include the generic and brand name in many instances.
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