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Brand Names: Zegerid

Generic Name: omeprazole and sodium bicarbonate (Pronunciation: oh ME pray zol and SO dee um by KAR bon ate)

• What is omeprazole and sodium bicarbonate (Zegerid)?
• What are the possible side effects of omeprazole and sodium bicarbonate (Zegerid)?
• What is the most important information I should know about omeprazole and sodium bicarbonate (Zegerid)?
• What should I discuss with my health care provider before taking omeprazole and sodium bicarbonate (Zegerid)?
• How should I take omeprazole and sodium bicarbonate (Zegerid)?
• What happens if I miss a dose (Zegerid)?
• What happens if I overdose (Zegerid)?
• What should I avoid while taking omeprazole and sodium bicarbonate (Zegerid)?
• What other drugs will affect omeprazole and sodium bicarbonate (Zegerid)?
• Where can I get more information?

What is omeprazole and sodium bicarbonate (Zegerid)?

Omeprazole decreases the amount of acid your stomach produces. Sodium bicarbonate is an antacid that raises the pH in your stomach to keep the omeprazole from breaking down in stomach acid.

Omeprazole and sodium bicarbonate is used to treat ulcers, gastroesophageal reflux disease (GERD), and other conditions involving excessive stomach acid production.

Omeprazole and sodium bicarbonate may also be used for other purposes not listed in this medication guide.

What are the possible side effects of omeprazole and sodium bicarbonate (Zegerid)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

• easy bruising or bleeding, unusual weakness; or
• fast, slow, or uneven heartbeat.

Less serious side effects may include:

• headache;
• nausea, stomach pain; or
• diarrhea or constipation;
• white patches or sores inside your mouth or on your lips;
• mild fever.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about omeprazole and sodium bicarbonate (Zegerid)?

Omeprazole and sodium bicarbonate can change the way your body absorbs or eliminates certain other drugs. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

This medication contains sodium bicarbonate, a form of salt. Each capsule contains the equivalent of 300 mg of sodium. Each packet of powder contains the equivalent of 460 mg of sodium. If you are on a low-salt or low-sodium diet, you may not be able to use omeprazole and sodium bicarbonate. Talk with your doctor.

Take this medicine on an empty stomach, at least 1 hour before eating a meal. If this medicine is given to a person who is fed through a nasogastric (NG) tube, the feeding should be stopped at least 3 hours before giving the medicine. Do not restart nasogastric feeding for at least 1 hour after giving omeprazole and sodium bicarbonate.

Take the capsule or powder for oral suspension only with water. Do not use any other type of liquid or food.

The 20-mg and the 40-mg forms of this medicine contain the same strength of sodium bicarbonate. Do not use two 20-mg capsules to equal one 40-mg capsule. Do not use two 20-mg powder packets to equal one 40-mg powder packet. If you do not use the exact capsule or powder packet your doctor has prescribed, you may receive too much sodium bicarbonate.