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Zemplar

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Zemplar Injection

ZEMPLAR®
(paricalcitol) Injection

Fliptop Vial

DRUG DESCRIPTION

Paricalcitol, USP, the active ingredient in Zemplar Injection (paricalcitol injection fliptop vial) , is a synthetically manufactured analog of calcitriol, the metabolically active form of vitamin D indicated for the prevention and treatment of secondary hyperparathyroidism associated with chronic kidney disease(CKD) Stage 5. Zemplar is available as a sterile, clear, colorless, aqueous solution for intravenous injection. Each mL contains paricalcitol, 2 mcg or 5 mcg and the following inactive ingredients: alcohol, 20% (v/v) and propylene glycol, 30% (v/v).

Paricalcitol is a white powder chemically designated as 19-nor-1α,3β,25-trihydroxy-9,10-secoergosta­5(Z),7(E),22(E)-triene and has the following structural formula:

ZEMPLAR® (paricalcitol)  Structural Formula Illustration

Molecular formula is C27H44O3.

Molecular weight is 416.64.

What are the precautions when taking paricalcitol injection fliptop vial (Zemplar Injection)?

Before using paricalcitol, tell your doctor or pharmacist if you are allergic to it; or to other vitamin D products; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: high levels of calcium (hypercalcemia), high levels of vitamin D (hypervitaminosis D).

Before using this medication, tell your doctor or pharmacist your medical history, especially of: regular use/abuse of alcohol, brain problems (e.g., seizures, brain injury), heart problems (e.g., arrhythmias, coronary artery disease), liver...

Read All Potential Precautions of Zemplar Injection »

Last reviewed on RxList: 5/20/2011
This monograph has been modified to include the generic and brand name in many instances.

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Zemplar Injection - User Reviews

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Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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