"The US Food and Drug Administration (FDA) has approved atazanavir and cobicistat (Evotaz, Bristol-Myers Squibb) for treatment of adults with human immunodeficiency virus (HIV-1) infection.
Atazanavir/cobicistat is a fixed-dos"...
Zerit Patient Information Including Side Effects
Brand Names: Zerit
Generic Name: stavudine (Pronunciation: STA vue deen)
- What is stavudine (Zerit)?
- What are the possible side effects of stavudine (Zerit)?
- What is the most important information I should know about stavudine (Zerit)?
- What should I discuss with my healthcare provider before taking stavudine (Zerit)?
- How should I take stavudine (Zerit)?
- What happens if I miss a dose (Zerit)?
- What happens if I overdose (Zerit)?
- What should I avoid while taking stavudine (Zerit)?
- What other drugs will affect stavudine (Zerit)?
- Where can I get more information?
What is stavudine (Zerit)?
Stavudine is an antiviral medication that prevents human immunodeficiency virus (HIV) cells from multiplying in your body.
Stavudine is used to treat HIV, which causes the acquired immunodeficiency syndrome (AIDS). Stavudine is not a cure for HIV or AIDS.
Stavudine may also be used for purposes not listed in this medication guide.
Zerit 15 mg
red/yellow, capsule, imprinted with BMS 1964, 15
Zerit 20 mg
orange, capsule, imprinted with BMS 1965, 20
Zerit 30 mg
capsule, orange, imprinted with BMS 1966, 30
Zerit 40 mg
orange, capsule, imprinted with BMS 1967, 40
What are the possible side effects of stavudine (Zerit)?
Stop using stavudine and get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
This medication may cause lactic acidosis (a build-up of lactic acid in the body, which can be fatal). Lactic acidosis can start slowly and get worse over time. Get emergency medical help if you have even mild symptoms of lactic acidosis, such as:
- muscle pain or weakness;
- numb or cold feeling in your arms and legs;
- trouble breathing;
- feeling dizzy, light-headed, tired, or very weak;
- stomach pain, nausea with vomiting; or
- fast or uneven heart rate.
Stop using stavudine and call your doctor at once if you have a serious side effect such as:
- signs of a new infection such as fever, chills, sore throat, flu symptoms, easy bruising or unusual bleeding, loss of appetite, mouth sores;
- severe pain in your upper stomach spreading to your back, nausea and vomiting, fast heart rate;
- upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
- increased sweating, tremors in your hands, anxiety, feeling irritable, sleep problems (insomnia);
- diarrhea, unexplained weight loss, menstrual changes, impotence, loss of interest in sex;
- swelling in your neck or throat (enlarged thyroid);
- weakness, numbness, pain, or prickly feeling in your hands or feet;
- problems with walking, breathing, speech, swallowing, or eye movement; or
- severe lower back pain, loss of bladder or bowel control.
Less serious side effects may include:
- mild nausea;
- mild skin rash; or
- changes in the shape or location of body fat (especially in your arms, legs, face, neck, breasts, and trunk).
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Read the Zerit (stavudine) Side Effects Center for a complete guide to possible side effects
What is the most important information I should know about stavudine (Zerit)?
Stavudine should not be taken together with any HIV combination that includes zidovudine (Combivir, Retrovir, or Trizivir).
Some people develop lactic acidosis while taking stavudine. Early symptoms may get worse over time and this condition can be fatal. Get emergency medical help if you have even mild symptoms such as: muscle pain or weakness, numb or cold feeling in your arms and legs, trouble breathing, stomach pain, nausea with vomiting, fast or uneven heart rate, dizziness, or feeling very weak or tired.
Stavudine can also cause severe or life-threatening effects on your liver or pancreas. Call your doctor at once if you have any of these symptoms while taking stavudine: severe pain in your upper stomach spreading to your back, nausea and vomiting, fast heart rate, itching, loss of appetite, dark urine, clay-colored stools, or jaundice (yellowing of the skin or eyes).
Before taking stavudine, tell your doctor if you have kidney disease, liver disease, a history of pancreatitis, or if you have used a medicine similar to stavudine in the past, such as abacavir (Ziagen), didanosine (Videx), emtricitabine (Atripla, Complera, Emtriva, Truvada), lamivudine (Epivir, Combivir, Epzicom, Trizivir), tenofovir (Viread), zalcitabine (Hivid), or zidovudine (Retrovir).
Additional Zerit Information
- Zerit Drug Interactions Center: stavudine oral
- Zerit Side Effects Center
- Zerit Overview including Precautions
- Zerit FDA Approved Prescribing Information including Dosage
Zerit - User Reviews
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