"SILVER SPRING, MD â€” The US Food and Drug Administration (FDA) is warning of several treatment-related serious adverse events in association with implantable left ventricular assist devices (LVADs) in heart-failure patients.
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Lisinopril is an oral long-acting angiotensin converting enzyme (ACE) inhibitor. Lisinopril, a synthetic peptide derivative, is chemically described as (S)-1-[N2-(1-carboxy-3-phenylpropyl)-L-lysyl]-L-proline dihydrate. Its empirical formula is C21H31N3O52H2O and its structural formula is:
Lisinopril is a white to off-white, crystalline powder, with a molecular weight of 441.53. It is soluble in water and sparingly soluble in methanol and practically insoluble in ethanol.
Zestril is supplied as 2.5 mg, 5 mg, 10 mg, 20 mg, 30 mg and 40 mg tablets for oral administration.
2.5 mg tablets -calcium phosphate, magnesium stearate, mannitol, starch.
5, 10, 20 and 30 mg tablets -calcium phosphate, magnesium stearate, mannitol, red ferric oxide, starch.
40 mg tablets -calcium phosphate, magnesium stearate, mannitol, starch, yellow ferric oxide.
What are the possible side effects of lisinopril (Prinivil, Zestril)?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; severe stomach pain, difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have a serious side effect such as:
- feeling like you might pass out;
- urinating less than usual or not at all;
- swelling, rapid weight gain;
- fever, chills, body aches, flu symptoms;
- tired feeling, muscle weakness, and pounding or uneven heartbeats;
- psoriasis (raised, silvery flaking of the skin);
What are the precautions when taking lisinopril (Zestril)?
Before taking lisinopril, tell your doctor or pharmacist if you are allergic to it; or to other ACE inhibitors (such as benazepril); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: history of an allergic reaction which included swelling of the face/lips/tongue/throat (angioedema), blood filtering procedures (such as LDL apheresis, dialysis), high level of potassium in the blood, collagen vascular disease (such as lupus, scleroderma).
This drug may make you dizzy. Do not drive, use machinery, or do any activity that requires alertness until you are...
Last reviewed on RxList: 7/14/2014
This monograph has been modified to include the generic and brand name in many instances.
Additional Zestril Information
Zestril - User Reviews
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