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Zioptan

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Zioptan

ZIOPTAN™
(tafluprost) Ophthalmic Solution

DRUG DESCRIPTION

Tafluprost is a fluorinated analog of prostaglandin F2α. The chemical name for tafluprost is 1methylethyl (5Z)-7-{(1R, 2R, 3R, 5S)-2-[(1E)-3,3-difluoro-4-phenoxy-1-butenyl}-3,5-dihydroxycyclopentyl]5-heptenoate. The molecular formula of tafluprost is C25H34F2O5 and its molecular weight is 452.53.

Its structural formula is:

ZIOPTAN™  (tafluprost) Structural Formula Illustration

Tafluprost is a colorless to light yellow viscous liquid that is practically insoluble in water.

ZIOPTAN (tafluprost ophthalmic solution) 0.0015% is supplied as a sterile solution of tafluprost with a pH range of 5.5 - 6.7 and an Osmolality range of 260 – 300 mOsmol/kg.

ZIOPTAN contains Active: tafluprost 0.015 mg/mL; Inactives: glycerol, sodium dihydrogen phosphate dihydrate, disodium edetate, polysorbate 80, hydrochloric acid and/or sodium hydroxide (to adjust pH) and Water for Injection.

ZIOPTAN does not contain a preservative.

Last reviewed on RxList: 2/27/2012
This monograph has been modified to include the generic and brand name in many instances.

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