Pentetate zinc trisodium injection contains the sodium salt of zinc diethylenetriaminepentaacetate. Pentetate zinc trisodium is also known as trisodium zinc diethylene-triaminepentaacetate and is commonly referred to as Zn-DTPA (pentetate zinc trisodium injection) . It has a molecular formula of Na₃ZnC₁₄H₁₈N₃O₁₀ and a molecular weight of 522.7 Daltons. It is represented by the following structural formula:

Zn-DTPA (pentetate zinc trisodium injection) is supplied as a clear, colorless, hyperosmolar (1260 mOsmol/kg) solution in a colorless ampoule containing 5 mL. The ampoule contents are sterile, non-pyrogenic and suitable for intravenous administration. Each mL of solution contains the equivalent of 200 mg pentetate zinc trisodium (obtained from 150.51 mg pentetic acid, 31.14 mg zinc oxide and NaOH) and water for injection, USP. The pH of the solution is adjusted with NaOH and is between 6.5 - 7.5.

Last reviewed on RxList: 3/9/2009
This monograph has been modified to include the generic and brand name in many instances.