July 29, 2016
Recommended Topic Related To:


"The U.S. Food and Drug Administration today approved Differin Gel 0.1% (adapalene), a once-daily topical gel for the over-the-counter (OTC) treatment of acne. Differin Gel 0.1% is approved for use in people 12 years of age and older.




(5.75% benzoyl peroxide)

Benzoyl Peroxide in a Urea Vehicle


ZoDerm® 5.75% Benzoyl Peroxide Hydrating Wash™ is intended for topical administration and contains Benzoyl Peroxide for use in the treatment of acne vulgaris. Benzoyl Peroxide is an oxidizing agent that possesses antibacterial properties and is classified as a keratolytic. Benzoyl Peroxide (C14H10O4) is represented by the following chemical structure:

  (Benzoyl Peroxide) Structural Formula Illustration

Each mL of ZoDerm® 5.75% Benzoyl Peroxide Hydrating Wash™ contains 57.5 mg of benzoyl peroxide in an emulsion-based formulation consisting of: purified water,urea(100/o),sodium lauryl sulfoacetate, glycerin, propylene glycol, magnesium aluminum silicate, disodium oleamido MEA-sulfosuccinate, sodium octoxynol-2 ethane sulfonate, cetyl alcohol, laureth-12, glyceryl stearate/PEG-100 stearate, xanthan gum, citric acid, sodium citrate, carbomer and disodium EDTA.

What are the possible side effects of benzoyl peroxide and urea topical (Zoderm)?

Serious side effects are not likely to occur. Stop using benzoyl peroxide and urea topical and seek emergency medical attention if you experience a rare but serious allergic reaction (shortness of breath; closing of the throat; swelling of the lips, face, or tongue; or hives).

Some skin burning, stinging, tingling, itching, redness, dryness, peeling, or irritation of the treated area may be experienced while using benzoyl peroxide and urea topical. Contact your doctor if these side effects are excessive. Less frequent application of benzoyl peroxide and urea...

Read All Potential Side Effects and See Pictures of Zoderm »

Last reviewed on RxList: 9/27/2011
This monograph has been modified to include the generic and brand name in many instances.

Report Problems to the Food and Drug Administration


You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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