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In this Article

• What is ondansetron injection (Zofran Injection)?
• What are the possible side effects of ondansetron injection (Zofran Injection)?
• What is the most important information I should know about ondansetron injection (Zofran Injection)?
• What should I discuss with my health care provider before using ondansetron injection (Zofran Injection)?
• How is ondansetron injection used (Zofran Injection)?
• What happens if I miss a dose (Zofran Injection)?
• What happens if I overdose (Zofran Injection)?
• What should I avoid while receiving ondansetron injection (Zofran Injection)?
• What other drugs will affect ondansetron injection (Zofran Injection)?
• Where can I get more information?

What happens if I miss a dose (Zofran Injection)?

Call your doctor for instructions.

What happens if I overdose (Zofran Injection)?

Seek emergency medical attention if you think you have received too much of this medicine.

Symptoms of an ondansetron overdose may include sudden loss of vision, severe constipation, feeling light-headed, fainting.

What should I avoid while receiving ondansetron injection (Zofran Injection)?

Avoid using other medicines that make you sleepy (such as cold medicine, pain medication, muscle relaxers, and medicine for seizures, depression or anxiety). They can add to sleepiness caused by ondansetron injection.

Ondansetron injection can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

What other drugs will affect ondansetron injection (Zofran Injection)?

Before receiving ondansetron injection, tell your doctor if you are using any of the following drugs:

• phenytoin (Dilantin), phenobarbital (Luminal);
• carbamazepine (Carbatrol, Tegretol);
• tramadol (Ultram);
• rifabutin (Mycobutin), rifampin (Rifadin, Rimactane, Rifater);
• amiodarone (Cordarone), mibefradil (Posicor);
• cimetidine (Tagamet);
• clarithromycin (Biaxin), erythromycin (E.E.S., E-Mycin, Ery-Tab); or
• HIV medicines such as indinavir (Crixivan), saquinavir (Invirase), ritonavir (Norvir), or nelfinavir (Viracept).

If you are using any of these drugs, you may not be able to use ondansetron injection, or you may need dosage adjustments or special tests during treatment.

There may be other drugs not listed that can affect ondansetron injection. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Where can I get more information?

Your doctor or pharmacist has more information about ondansetron injection written for health professionals that you may read.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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