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Zolinza Patient Information Including Side Effects

Brand Names: Zolinza

Generic Name: vorinostat (Pronunciation: vor IN o stat)

What is vorinostat (Zolinza)?

Vorinostat is used to treat skin problems caused by cutaneous T-cell lymphoma.

Vorinostat is usually given after other treatments have been tried without successful treatment.

Vorinostat may also be used for purposes not listed in this medication guide.

What are the possible side effects of vorinostat (Zolinza)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using vorinostat and call your doctor at once if you have a serious side effect such as:

  • chest pain, sudden cough, wheezing, rapid breathing;
  • pain, swelling, warmth, or redness in one or both legs;
  • fever, chills, body aches, flu symptoms, sores in your mouth and throat;
  • pale skin, feeling light-headed or short of breath, rapid heart rate, trouble concentrating;
  • easy bruising, unusual bleeding (nose, mouth, vagina, or rectum), purple or red pinpoint spots under your skin;
  • severe or ongoing vomiting or diarrhea;
  • bloody, black, or tarry stools;
  • coughing up blood or vomit that looks like coffee grounds;
  • feeling very thirsty or hot, being unable to urinate, heavy sweating, or hot and dry skin; or
  • high blood sugar (increased thirst, increased urination, hunger, dry mouth, fruity breath odor, drowsiness, dry skin, blurred vision).

Less serious side effects may include:

  • nausea, constipation, diarrhea;
  • loss of appetite, weight loss;
  • headache, tired feeling;
  • itching, chills;
  • dry mouth;
  • hair loss;
  • altered sense of taste;
  • muscle spasms; or
  • cold symptoms such as stuffy nose, sneezing, cough, sore throat.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the Zolinza (vorinostat) Side Effects Center for a complete guide to possible side effects

What is the most important information I should know about vorinostat (Zolinza)?

You should not use this medication if you are allergic to vorinostat, or if you have severe liver disease.

Do not use vorinostat if you are pregnant. It could harm the unborn baby.

You should not breast-feed while you are using vorinostat.

Drink at least 2 liters of water each day to keep from getting dehydrated while you are taking vorinostat. Tell your doctor if you have severe vomiting or diarrhea during treatment.

Do not crush or open a vorinostat capsule. Swallow it whole. The medicine inside the capsule can be dangerous if it gets in your eyes, mouth, or nose, or on your skin. If this occurs, wash your skin with soap and water or rinse your eyes with water. Ask your doctor or pharmacist how to safely handle and dispose of a broken tablet or capsule.

You may need regular medical tests to be sure this medication is not causing harmful effects. Visit your doctor regularly.

Stop using vorinostat and call your doctor at once if you have chest pain, sudden cough, wheezing, rapid breathing, coughing up blood, swelling or warmth in one or both legs, fever, chills, mouth sores, easy bruising or bleeding, bloody or tarry tools, or severe vomiting or diarrhea.

Side Effects Centers

Zolinza - User Reviews

Zolinza User Reviews

Now you can gain knowledge and insight about a drug treatment with Patient Discussions.

Here is a collection of user reviews for the medication Zolinza sorted by most helpful. Patient Discussions FAQs

Report Problems to the Food and Drug Administration


You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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