Zolpimist (Zolpidem Tartrate Oral Spray) Drug Information: Description, User Reviews, Drug Side Effects, Interactions

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February 9, 2012

Zolpimist

Insomnia Treatment (Sleep Aids and Stimulants) »

What is insomnia and what causes it?

Insomnia is difficulty in falling or staying asleep, the absence of restful sleep, or poor quality of sleep. Insomnia is a symptom and not a disease. The most common causes of insomnia are:

medications,
psychological conditions (for example, depression, anxiety),
environmental changes (travel, jet lag, or altitude changes), and
stressful events or a stressful lifestyle.

Insomnia can also be caused by poor sleeping habits such as excessive daytime naps or caffeine consumption and poor sleep hygiene.

The National Center for Sleep Disorders Research at the National Institutes of Health estimates 30%-40% of adults report some symptoms of insomnia each year, and about 10%-15% report they have chronic insomnia.

Insomnia may be classified by how long the symptoms are ...

Read the Insomnia Treatment (Sleep Aids and Stimulants) article »

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Zolpimist

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Zolpimist
(zolpidem tartrate) Oral Spray

DRUG DESCRIPTION

Zolpimist contains zolpidem tartrate, a non-benzodiazepine hypnotic of the imidazopyridine class. Chemically, zolpidem is N,N,6-trimethyl-2-p-tolylimidazo[1,2-a] pyridine-3-acetamide L-(+)tartrate (2:1). It has the following structure:

Zolpimist (zolpidem tartrate) Structural Formula Illustration

Zolpidem tartrate is a white to off-white crystalline powder that is sparingly soluble in water, alcohol, and propylene glycol. It has a molecular weight of 764.89.

Zolpimist (zolpidem tartrate oral spray) is available as an oral solution designed to be sprayed directly into the mouth over the tongue. Each metered actuation of Zolpimist delivers 5 mg of zolpidem tartrate in 100 μL. Two actuations deliver 10 mg of zolpidem tartrate. Zolpimist (zolpidem tartrate oral spray) includes the following inactive ingredients: artificial cherry flavor, benzoic acid, citric acid monohydrate, hydrochloric acid, neotame, propylene glycol, and purified water.

What are the precautions when taking zolpidem tartrate oral spray (Zolpimist)?

Before using zolpidem, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney disease, liver disease, mental/mood problems (such as depression, thoughts of suicide), personal or family history of regular use/abuse of drugs/alcohol/other substances, lung/breathing problems (such as chronic obstructive pulmonary disease-COPD, sleep apnea), a certain muscle disease (myasthenia gravis).

Since this drug makes you drowsy, do not drive, use machinery, or do any activity that requires alertness...

Read All Potential Precautions of Zolpimist »

Last reviewed on RxList: 2/23/2009
This monograph has been modified to include the generic and brand name in many instances.