Zolvit (Hydrocodone Bitartrate and Acetaminophen Oral Solution) Drug Information: Description, User Reviews, Drug Side Effects, Interactions

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May 27, 2012

Zolvit

Pain Management: Musculoskeletal Pain »

What Causes Musculoskeletal Pain?

The causes of musculoskeletal pain are varied. Muscle tissue can be damaged with the wear and tear of daily activities. Trauma to an area (jerking movements, auto accidents, falls, fractures, sprains, dislocations, and direct blows to the muscle) also can cause musculoskeletal pain. Other causes of pain include postural strain, repetitive movements, overuse, and prolonged immobilization. Changes in posture or poor body mechanics may bring about spinal alignment problems and muscle shortening, therefore causing other muscles to be misused and become painful.

What Are the Symptoms of Musculoskeletal Pain?

People with musculoskeletal pain sometimes complain that their entire bodies ache. Their muscles may feel like they have been pulled or overworked. Sometimes the muscles twitch or burn. Symptoms vary from person to person, but the common symptoms are:

Pain
Fatigue
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Read the Pain Management: Musculoskeletal Pain article »

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Zolvit™
(hydrocodone bitartrate (10 mg) and acetaminophen (300 mg) per 15 mL) Oral Solution

DRUG DESCRIPTION

Hydrocodone bitartrate and acetaminophen is supplied in liquid form for oral administration.

WARNING: May be habit-forming

(see PRECAUTIONS, PATIENT INFORMATION, and Drug Abuse and Dependence).

Hydrocodone bitartrate is an opioid analgesic and antitussive and occurs as fine, white crystals or as a crystalline powder. It is affected by light. The chemical name is 4,5α-epoxy-3-methoxy-17- methylmorphinan-6-one tartrate (1:1) hydrate (2:5). It has the following structural formula:

Hydrocodone bitartrate Structural Formula Illustration

Acetaminophen, 4'-hydroxyacetanilide, a slightly bitter, white, odorless, crystalline powder, is a non-opiate, non-salicylate analgesic and antipyretic. It has the following structural formula:

Acetaminophen Structural Formula Illustration

ZOLVIT™ (hydrocodone bitartrate and acetaminophen oral solution contains):

	Per 5 mL	Per 15 mL
Hydrocodone Bitartrate	3.33 mg	10 mg
Acetaminophen	100 mg	300 mg
Alcohol	7%	7%

In addition, the liquid contains the following inactive ingredients: citric acid anhydrous, ethyl maltol, glycerin, methylparaben, propylene glycol, propylparaben, purified water, saccharin sodium, sorbitol solution, sucrose, with D&C Red #33 and FD&C Red #40 as coloring and natural and artificial flavoring.

Last reviewed on RxList: 8/15/2011
This monograph has been modified to include the generic and brand name in many instances.