"Sept. 1, 2011 -- The FDA warns that the osteoporosis drug Reclast (zoledronic acid) raises the risk of kidney failure.
The warning is targeted at patients who already suffer from kidney impairment. It's also aimed at those who are tak"...
- Patient Information:
Details with Side Effects
- Patients should be instructed to tell their doctor if they have kidney problems before being given Zometa.
- Patients should be informed of the importance of getting their blood tests (serum creatinine) during the course of their Zometa therapy.
- Zometa should not be given if the patient is pregnant or plans to become pregnant, or if she is breast-feeding.
- Patients should be advised to have a dental examination prior to treatment with Zometa and should avoid invasive dental procedures during treatment.
- Patients should be informed of the importance of good dental hygiene and routine dental care.
- Patients with multiple myeloma and bone metastasis of solid tumors should be advised to take an oral calcium supplement of 500 mg and a multiple vitamin containing 400 IU of Vitamin D daily.
- Patients should be advised to report any thigh, hip or groin pain. It is unknown whether the risk of atypical femur fracture continues after stopping therapy.
- Patients should be aware of the most common side effects including: anemia, nausea, vomiting, constipation, diarrhea, fatigue, fever, weakness, lower limb edema, anorexia, decreased weight, bone pain, myalgia, arthralgia, back pain, malignant neoplasm aggravated, headache, dizziness, insomnia, paresthesia, dyspnea, cough, and abdominal pain.
- There have been reports of bronchoconstriction in aspirin-sensitive patients receiving bisphosphonates, including zoledronic acid. Before being given zoledronic acid, patients should tell their doctor if they are aspirin-sensitive.
Last reviewed on RxList: 11/28/2012
This monograph has been modified to include the generic and brand name in many instances.
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