Migraines and Headaches Resources
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A Headache is defined as a pain in the head or upper neck. It is one of the most common locations of pain in the body and has many causes.
Headaches have numerous causes, and in 2007 the International Headache Society agreed upon an updated classification system for headache. Because so many people suffer from headaches and because treatment sometimes is difficult, it is hoped that the new classification system will allow health care practitioners come to a specific diagnosis as to the type of headache and to provide better and more effective treatment.
There are three major categories of headaches:
Primary headaches include migraine, tension, and cluster headaches, ...
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ZOMIG®
(zolmitriptan) Nasal spray
ZOMIG® (zolmitriptan) Nasal Spray contains zolmitriptan, which is a selective 5-hydroxy- tryptamine1B/1D (5-HT1B/1D) receptor agonist. Zolmitriptan is chemically designated as (S)-4-[[3-[2-(dimethylamino) ethyl]-1H-indol-5-yl]methyl]-2-oxazolidinone and has the following chemical structure:
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The empirical formula is C16H21N3O2, representing a molecular weight of 287.36. Zolmitriptan is a white to almost white powder that is readily soluble in water. ZOMIG (zolmitriptan nasal spray) Nasal Spray is supplied as a clear to pale yellow solution of zolmitriptan, buffered to a pH 5.0. Each ZOMIG Nasal Spray contains 5 mg of zolmitriptan in a 100-μL unit dose aqueous buffered solution containing citric acid, anhydrous, USP, disodium phosphate dodecahydrate USP and purified water USP.
ZOMIG (zolmitriptan nasal spray) Nasal Spray is hypertonic. The osmolarity of ZOMIG (zolmitriptan nasal spray) Nasal Spray 5 mg is 420 to 470 mOsmol.
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using zolmitriptan and call your doctor at once if you have any of these serious side effects:
Read All Potential Side Effects and See Pictures of Zomig Nasal Spray »
See also How to Use section.
Before using zolmitriptan, tell your doctor or pharmacist if you are allergic to it; or to other "triptan" migraine drugs; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: heart disease (e.g., chest pain, heart attack, irregular heartbeat, coronary artery disease, vasospasm), blood flow problems in the brain (e.g., stroke, transient ischemic attack), blood vessel disease (e.g., peripheral vascular disease, ischemic bowel disease), uncontrolled high blood pressure...
Last reviewed on RxList: 12/22/2008
This monograph has been modified to include the generic and brand name in many instances.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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