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Zomig Nasal Spray

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Zomig Nasal Spray

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ZOMIG®
(zolmitriptan) Nasal spray

DRUG DESCRIPTION

ZOMIG® (zolmitriptan) Nasal Spray contains zolmitriptan, which is a selective 5-hydroxy- tryptamine1B/1D (5-HT1B/1D) receptor agonist. Zolmitriptan is chemically designated as (S)-4-[[3-[2-(dimethylamino) ethyl]-1H-indol-5-yl]methyl]-2-oxazolidinone and has the following chemical structure:

ZOMIG® (zolmitriptan) Structural Formula Illustration

The empirical formula is C16H21N3O2, representing a molecular weight of 287.36. Zolmitriptan is a white to almost white powder that is readily soluble in water. ZOMIG (zolmitriptan nasal spray) Nasal Spray is supplied as a clear to pale yellow solution of zolmitriptan, buffered to a pH 5.0. Each ZOMIG Nasal Spray contains 5 mg of zolmitriptan in a 100-μL unit dose aqueous buffered solution containing citric acid, anhydrous, USP, disodium phosphate dodecahydrate USP and purified water USP.

ZOMIG (zolmitriptan nasal spray) Nasal Spray is hypertonic. The osmolarity of ZOMIG (zolmitriptan nasal spray) Nasal Spray 5 mg is 420 to 470 mOsmol.

What are the possible side effects of nasal zolmitriptan (Zomig)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using zolmitriptan and call your doctor at once if you have a serious side effect such as:

  • feeling of pain or tightness in your jaw, neck, or throat;
  • chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling;
  • sudden numbness or weakness, especially on one side of the body;
  • sudden severe headache, confusion, problems with vision,...

Read All Potential Side Effects and See Pictures of Zomig Nasal Spray »

What are the precautions when taking zolmitriptan nasal spray (Zomig Nasal Spray)?

See also How to Use section.

Before using zolmitriptan, tell your doctor or pharmacist if you are allergic to it; or to other "triptan" migraine drugs; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: heart disease (e.g., chest pain, heart attack, irregular heartbeat, coronary artery disease, vasospasm), blood flow problems in the brain (e.g., stroke, transient ischemic attack), blood vessel disease (e.g., peripheral vascular disease, ischemic bowel disease), uncontrolled high blood pressure...

Read All Potential Precautions of Zomig Nasal Spray »

Last reviewed on RxList: 12/22/2008
This monograph has been modified to include the generic and brand name in many instances.

Zomig Nasal Spray - User Reviews

Zomig Nasal Spray User Reviews

Now you can gain knowledge and insight about a drug treatment with Patient Discussions.

Here is a collection of user reviews for the medication Zomig Nasal Spray sorted by most helpful. Patient Discussions FAQs

Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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