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Brand Names: Zomig

Generic Name: zolmitriptan (nasal) (Pronunciation: ZOL mi TRIP tan)

• What is zolmitriptan (Zomig Nasal Spray)?
• What are the possible side effects of nasal zolmitriptan (Zomig Nasal Spray)?
• What is the most important information I should know about nasal zolmitriptan nasal (Zomig Nasal Spray)?
• What should I discuss with my healthcare provider before using nasal zolmitriptan (Zomig Nasal Spray)?
• How should I use nasal zolmitriptan (Zomig Nasal Spray)?
• What happens if I miss a dose (Zomig Nasal Spray)?
• What happens if I overdose (Zomig Nasal Spray)?
• What should I avoid while using nasal zolmitriptan (Zomig Nasal Spray)?
• What other drugs will affect nasal zolmitriptan (Zomig Nasal Spray)?
• Where can I get more information?

What is zolmitriptan (Zomig Nasal Spray)?

Zolmitriptan is a headache medicine. It is believed to work by narrowing the blood vessels around the brain. Zolmitriptan also reduces substances in the body that can trigger headache pain, nausea, sensitivity to light and sound, and other migraine symptoms.

Zolmitriptan is used to treat migraine headaches.

Zolmitriptan will only treat a headache that has already begun. It will not prevent headaches or reduce the number of attacks.

Zolmitriptan should not be used to treat common tension headaches or any headache that seems to be different from your usual migraine headaches. Use this medication only if your condition has been confirmed by a doctor as migraine headaches.

Zolmitriptan may also be used for other purposes not listed in this medication guide.

What are the possible side effects of nasal zolmitriptan (Zomig Nasal Spray)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using zolmitriptan and call your doctor at once if you have any of these serious side effects:

• chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling;
• sudden numbness or weakness, especially on one side of the body;
• sudden headache, confusion, problems with vision, speech, or balance;
• pain or swelling in one or both legs;
• fast or pounding heartbeats, dizziness;
• sudden and severe stomach pain and bloody diarrhea;
• numbness or tingling and a pale or blue-colored appearance in your fingers or toes; or
• (if you are also taking an antidepressant) - agitation, high fever, sweating, nausea, vomiting, diarrhea, loss of balance or coordination, overactive reflexes, hallucinations, fainting;

Less serious side effects may include:

• dry mouth, unusual or unpleasant taste in your mouth;
• pain, tingling, or discomfort in or around your nose;
• mild nausea or stomach pain;
• feeling of pain or pressure in your neck or throat;
• drowsiness, weakness;
• headache; or
• sleep problems (insomnia).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about nasal zolmitriptan nasal (Zomig Nasal Spray)?

Do not use zolmitriptan within 24 hours before or after using another migraine headache medicine, including zolmitriptan tablets, almotriptan (Axert), eletriptan (Relpax), frovatriptan (Frova), naratriptan (Amerge), rizatriptan (Maxalt, Maxalt-MLT), sumatriptan (Imitrex, Treximet), or ergot medicine such as dihydroergotamine (D.H.E. 45, Migranal), ergotamine (Ergomar, Ergostat, Cafergot, Ercaf, Wigraine), ergonovine (Ergotrate), methylergonovine (Methergine), or methysergide (Sansert).

You should not use this medication if you are allergic to zolmitriptan, or if you have a history of heart disease, angina (chest pain), blood circulation problems, ischemic bowel disease, severe liver disease, uncontrolled high blood pressure, or history of a heart attack or stroke.

Do not use zolmitriptan if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), tranylcypromine (Parnate), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or phenelzine (Nardil) in the past 14 days.

Before using zolmitriptan, tell your doctor if you have liver disease, high blood pressure, a heart rhythm disorder, coronary artery disease, or risk factors for coronary artery disease (such as diabetes, menopause, smoking, being overweight, having high blood pressure or high cholesterol, having a family history of coronary artery disease, being older than 40 and a man, or being a woman who has had a hysterectomy).

Before using zolmitriptan, tell your doctor if you are also taking an antidepressant such as citalopram (Celexa), duloxetine (Cymbalta), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem), fluvoxamine (Luvox), paroxetine (Paxil), sertraline (Zoloft), or venlafaxine (Effexor).

Zolmitriptan will only treat a headache that has already begun. It will not prevent headaches or reduce the number of attacks.

After using zolmitriptan spray, you must wait two (2) hours before using a second dose. Call your doctor if the first dose did not make your headache go away completely. Do not use more than 10 mg of zolmitriptan in 24 hours.