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Zosyn

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Zosyn Drug Center

Medical Editor: John P. Cunha, DO, FACOEP

Zosyn (piperacillin and tazobactam for injection, USP) is used to treat many different infections caused by bacteria, such as urinary tract infections, bone and joint infections, severe vaginal infections, stomach infections, skin infections, and pneumonia. It is a combination of two antibiotics. This medication is available in generic form. Common side effects include swelling, redness, pain, or soreness at the injection site. Dizziness, trouble sleeping, nausea, vomiting, diarrhea, or headache may also occur.

The usual total daily dose of Zosyn for adults is 3.375 g every six hours totaling 13.5 g (12.0 g piperacillin/1.5 g tazobactam). Zosyn may interact with probenecid, antibiotics, blood thinners, or any other medication used to prevent blood clots. Tell your doctor all medications you use. During pregnancy, Zosyn should be used only when prescribed. This medication may pass into breast milk. Consult your doctor before breast-feeding.

Our Zosyn (piperacillin and tazobactam for injection, USP) Drug Center provides a comprehensive view of available drug information as well as related drugs, user reviews, supplements, and diseases and conditions articles.

What is Prescribing information?

The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.

Zosyn Prescribing Information: Indications & Dosage

Piperacillin sodium - Structural Formula Illustration

ZOSYN (piperacillin and tazobactam for injection, USP) is indicated for the treatment of patients with moderate to severe infections caused by piperacillin-resistant, piperacillin/tazobactamsusceptible, β-lactamase producing strains of the designated microorganisms in the specified conditions listed below:

Appendicitis (complicated by rupture or abscess) and peritonitis caused by piperacillin-resistant, β-lactamase producing strains of Escherichia coli or the following members of the Bacteroides fragilis group: B. fragilis, B. ovat...

Read the complete drug monograph for Zosyn »

What is Patient information?

Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.

Zosyn Patient Information: Side Effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

  • diarrhea that is watery or bloody;
  • easy bruising or bleeding, unusual weakness;
  • dry mouth, increased thirst, confusion, increased urination, muscle pain or weakness, fast heart rate, feeling light-headed, fainting;
  • fever, chills, body aches, flu symptoms; or
  • seizure (convulsions).
...

Read the complete patient information for Zosyn »

What is Consumer information?

A concise overview of the drug for the patient or caregiver from First DataBank.

Zosyn Consumer Information: Uses

This medication is used to treat a wide variety of bacterial infections. This medication is a combination of 2 drugs. Piperacillin is a penicillin-type antibiotic that works by stopping the growth of bacteria. Tazobactam is an enzyme inhibitor (beta-lactamase inhibitor) that helps the piperacillin work better.

HOW TO USE: This medication is given by injection into a vein as directed by your doctor, usually every 6 hours. It should be injected slowly over at least 30 minutes. The dosage is based on your medical condition, age, weight, and response to...

Read the complete consumer information for Zosyn »

What is Zosyn Consumer Information?

Warnings - Uses - How to Use - Side Effects - Precautions - Drug Interactions and More

Zosyn Injection - User Reviews

Zosyn Injection User Reviews

Now you can gain knowledge and insight about a drug treatment with Patient Discussions.

Here is a collection of user reviews for the medication Zosyn Injection sorted by most helpful. Patient Discussions FAQs

Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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