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Zovirax Injection

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Zovirax Injection

Overdosage
Contraindications

OVERDOSE

Overdoses involving ingestions of up to 20 g have been reported. Adverse events that have been reported in association with overdosage include agitation, coma, seizures, and lethargy. Precipitation of acyclovir in renal tubules may occur when the solubility (2.5 mg/mL) is exceeded in the intratubular fluid. Overdosage has been reported following bolus injections or inappropriately high doses, and in patients whose fluid and electrolyte balance were not properly monitored. This has resulted in elevated BUN and serum creatinine, and subsequent renal failure. In the event of acute renal failure and anuria, the patient may benefit from hemodialysis until renal function is restored (see DOSAGE AND ADMINISTRATION).

CONTRAINDICATIONS

ZOVIRAX for Injection is contraindicated for patients who develop hypersensitivity to acyclovir or valacyclovir.

Last reviewed on RxList: 9/7/2007
This monograph has been modified to include the generic and brand name in many instances.

Overdosage
Contraindications
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Zovirax Injection - User Reviews

Zovirax Injection User Reviews

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