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(ondansetron) Oral Soluble Film
Read the Patient Information that comes with ZUPLENZ before you start taking it and each time you get a refill. There may be new information. This leaflet does not take the place of talking with your doctor about your medical condition or treatment.
What is ZUPLENZ?
ZUPLENZ is a prescription medicine that is used in adults to prevent nausea and vomiting:
- caused by certain cancer chemotherapy medicines, radiation therapy to your stomach-area (abdomen), or radiation therapy to your entire body.
- that may happen after surgery
In children aged 4 years and older, ZUPLENZ is only used to prevent nausea and vomiting due to certain cancer chemotherapy medicines.
It is not known if ZUPLENZ is safe and works in children to prevent nausea and vomiting with radiation therapy, or nausea and vomiting that may happen after surgery in children.
Who should not take ZUPLENZ?
Do not take ZUPLENZ if you take apomorphine hydrochloride (Apokyn).
Do not take ZUPLENZ if you have had an allergic reaction to ZUPLENZ or are allergic to any of its ingredients. See the end of this leaflet for a complete list of ingredients in ZUPLENZ.
Ask your doctor if you are not sure.
What should I tell my doctor before taking ZUPLENZ?
Before you take ZUPLENZ oral soluble film, tell you doctor if you:
- have liver problems
- have any other medical conditions
- are pregnant or plan to become pregnant. It is not known if ZUPLENZ will harm your unborn baby.
- are breastfeeding or plan to breastfeed. It is not known if ZUPLENZ passes into your breast milk.
Tell your doctor about all the medicines you take, including prescription and non-prescription, vitamins, and herbal supplements. Some medicines may affect how ZUPLENZ works, and ZUPLENZ may affect how other medicines works. Using ZUPLENZ with certain other medicine may cause serious side effects. Especially tell your doctor if you take:
- apomorphine hydrochloride (Apokyn)
- tramadol hydrochloride (Ultram, Ultram ER, Ryzolt)
- another medicine for nausea and vomiting
Ask your doctor or pharmacist if you are not sure if your medicine is listed above.
Know the medicines you take. Keep a list of them to show to your doctor or pharmacist each time you start a new medicine.
How should I take ZUPLENZ?
Take ZUPLENZ exactly as your doctor tells you to take it.
An adult should help a young child use this medicine.
See the “Instructions for Use” at the end of this leaflet.
What should I avoid while taking ZUPLENZ?
Zuplenz may cause dizziness. Do not drive, operate machinery, or do other dangerous activities until you know how ZUPLENZ affects you.
What are the possible side effects of ZUPLENZ ?
ZUPLENZ may cause serious side effects, including:
- severe allergic reactions. Stop taking ZUPLENZ and
tell your doctor right away if you have any of these signs or symptoms of an
allergic reaction with ZUPLENZ:
- trouble breathing
- chest tightness or chest pain
- swelling of your mouth, face, lips, or tongue
- heart rhythm changes.
The most common side effects of ZUPLENZ are:
These are not all the possible side effects of ZUPLENZ. For more information, ask your doctor or your pharmacist.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1- 800-FDA-1088.
How should I store ZUPLENZ ?
- Store ZUPLENZ at room temperature, 68°F to 77°F (20°C to 25°C).
- Keep the film in the foil pouch until ready to use. Keep foil pouches in the carton.
- Use the film strip right away, after you take it from the pouch.
Keep ZUPLENZ and all medicines out of the reach of children.
General information about ZUPLENZ
Medicines are sometimes used for purposes other than those listed in Patient Information leaflets. Do not use ZUPLENZ for a condition for which it was not prescribed. Do not give ZUPLENZ to other people, even if they have the same condition that you have. It may harm them.
This Patient Information leaflet summarizes the most important information about ZUPLENZ. If you would like more information, talk with your doctor. You can ask your doctor or pharmacist for information about ZUPLENZ that is written for healthcare professionals. You can also visit www.ZUPLENZ.com or call 1-800-XXX-XXXX.
What are the ingredients in ZUPLENZ ?
Active ingredient: ondansetron
Inactive ingredients: butylated hydroxytoluene, calcium carbonate, colloidal silicon dioxide, erythritol, hyrdroxypropyl methylcellulose, monoammonium glycyrrhizinate, peppermint flavor, polyethylene oxide, sodium bicarbonate, sucralose, titanium oxide and xanthan gum.
Instructions for use
Oral Soluble Film
1. Keep the film in the foil pouch until ready to use. Use the film right away, after you take it from the pouch.
2. Make sure your hands are dry.
3. Fold the pouch along the dotted line to expose the tear notch. See Figure A.
4. While still folded, tear the pouch carefully along the edge. See Figure B.
5. Take the ZUPLENZ film strip from the pouch. See Figure C.
6. Put the ZUPLENZ film on top of your tongue, where it will dissolve in 4 to 20 seconds. See Figure D
7. Do not chew or swallow the film whole.
8. Swallow after the film dissolves. You may swallow the dissolved film with or without liquid.
9. Wash your hands after taking ZUPLENZ.
Last reviewed on RxList: 11/8/2013
This monograph has been modified to include the generic and brand name in many instances.
Additional Zuplenz Information
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