"Common colds are the main reason that children miss school and adults miss work. Each year in the United States, there are millions of cases of the common cold. Adults have an average of 2-3 colds per year, and children have even more.
(hydrocodone bitartrate, chlorpheniramine maleate, and pseudoephedrine hydrochloride) Oral Solution
ZUTRIPRO Oral Solution contains hydrocodone bitartrate (a semisynthetic centrally-acting opioid antitussive), Chlorpheniramine maleate (an antihistamine), and pseudoephedrine hydrochloride (an indirect sympathomimetic amine).
Each 5 mL dose of ZUTRIPRO Oral Solution contains: hydrocodone bitartrate, USP, 5 mg; Chlorpheniramine maleate, USP, 4 mg; and pseudoephedrine hydrochloride, USP, 60 mg.
ZUTRIPRO Oral Solution also contains: citric acid anhydrous, glycerin, grape flavor, methylparaben, propylene glycol, propylparaben, purified water, sodium citrate, sodium saccharin, and sucrose.
Hydrocodone bitartrate is morphinan-6-one, 4,5-epoxy-3-methoxy-17-methyl-, (5α)-, [R-(R*,R*)]-2,3-dihydroxybutanedioate (1:1), hydrate (2:5); also known as 4,5α-Epoxy-3-methoxy-17-methylmorphinan-6-one tartrate (1:1) hydrate (2:5); a fine white crystal or crystalline powder, which is derived from the opium alkaloid, thebaine; and may be represented by the following structural formula:
Molecular weight = 494.5
Chlorpheniramine maleate is 2-pyridinepropanamine, γ-(4-chlorophenyl)-N,N-dimethyl-, (Z)-2-butenedioate (1:1) and has the following chemical structure:
Molecular weight = 390.86
Pseudoephedrine hydrochloride is benzenemethanol, α-[l-(methylamino)ethyl]-, [S-(R*,R*)] hydrochloride and has the following chemical structure:
Molecular weight = 201.69
Last reviewed on RxList: 6/30/2011
This monograph has been modified to include the generic and brand name in many instances.
Additional Zutripro Information
- Zutripro Drug Interactions Center: cpm-pseudoephed-hydrocodone oral
- Zutripro Side Effects Center
- Zutripro FDA Approved Prescribing Information including Dosage
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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